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Rabbit Anti-ZWILCH Recombinant Antibody (CBWJZ-306) (CBMAB-Z0794-WJ)

This product is a rabbit antibody that recognizes ZWILCH. The antibody CBWJZ-306 can be used for immunoassay techniques such as: WB, IP.
See all ZWILCH antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBWJZ-306
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
Zwilch, kinetochore associated, homolog (Drosophila)
Introduction
Zwilch Kinetochore Protein
Entrez Gene ID
Human55055
Mouse68014
Rat691493
UniProt ID
HumanQ9H900
MouseQ8R060
RatD3ZG58
Alternative Names
KNTC1AP; hZwilch
Function
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:15824131).
Biological Process
Biological Process cell division Source:UniProtKB-KW
Biological Process mitotic spindle assembly checkpoint signaling Source:UniProtKB1 Publication
Biological Process protein localization to kinetochore Source:UniProtKB1 Publication
Cellular Location
Chromosome, centromere, kinetochore
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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