ZWILCH

Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:15824131).
Full Name
Zwilch, kinetochore associated, homolog (Drosophila)
Function
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:15824131).
Biological Process
Biological Process cell division Source:UniProtKB-KW
Biological Process mitotic spindle assembly checkpoint signaling Source:UniProtKB1 Publication
Biological Process protein localization to kinetochore Source:UniProtKB1 Publication
Cellular Location
Chromosome, centromere, kinetochore
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Anti-ZWILCH antibodies

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Rabbit Anti-ZWILCH Recombinant Antibody (CBWJZ-306) (CBMAB-Z0794-WJ)

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Target: ZWILCH
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBWJZ-306
Application*: WB, IP
Datasheet SDS

Mouse Anti-ZWILCH Recombinant Antibody (1C9) (CBMAB-Z0793-WJ)

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Target: ZWILCH
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1C9
Application*: E, WB
Datasheet SDS

Mouse Anti-ZWILCH Recombinant Antibody (1C10) (CBMAB-Z0792-WJ)

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Target: ZWILCH
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1C10
Application*: E, WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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