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ANXA1 Matched Antibody Pair (076) (APMAB-076LY)

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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-ANXA1 monoclonal antibody, 100 ug
Detection Antibody
Anti-ANXA1 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
Alternative Names
Annexin A1; Phospholipase A2 Inhibitory Protein; Chromobindin-9; Calpactin II; Calpactin-2; Annexin-1; ANX1;
Entrez Gene ID
UniProt ID
More Infomation

Galvão, I., de Carvalho, R. V., Vago, J. P., Silva, A. L., Carvalho, T. G., Antunes, M. M., ... & Teixeira, M. M. (2020). The role of annexin A1 in the modulation of the NLRP3 inflammasome. Immunology, 160(1), 78-89.

Machado, M. G., Tavares, L. P., Souza, G. V. S., Queiroz‐Junior, C. M., Ascenção, F. R., Lopes, M. E., ... & Sousa, L. P. (2020). The Annexin A1/FPR2 pathway controls the inflammatory response and bacterial dissemination in experimental pneumococcal pneumonia. The FASEB Journal, 34(2), 2749-2764.

Foo, S. L., Yap, G., Cui, J., & Lim, L. H. (2019). Annexin-A1–A blessing or a curse in cancer?. Trends in molecular medicine, 25(4), 315-327.

Okano, M., Oshi, M., Butash, A. L., Katsuta, E., Tachibana, K., Saito, K., ... & Takabe, K. (2019). Triple-negative breast cancer with high levels of annexin A1 expression is associated with mast cell infiltration, inflammation, and angiogenesis. International journal of molecular sciences, 20(17), 4197.

Han, G., Lu, K., Xu, W., Zhang, S., Huang, J., Dai, C., ... & Ye, J. (2019). Annexin A1‑mediated inhibition of inflammatory cytokines may facilitate the resolution of inflammation in acute radiation‑induced lung injury. Oncology letters, 18(1), 321-329.

Sheikh, M. H., & Solito, E. (2018). Annexin A1: uncovering the many talents of an old protein. International journal of molecular sciences, 19(4), 1045.

Zhu, J. F., Huang, W., Yi, H. M., Xiao, T. A., Li, J. Y., Feng, J., ... & Xiao, Z. Q. (2018). Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation. Cell death & disease, 9(12), 1-16.

Purvis, G. S., Chiazza, F., Chen, J., Azevedo-Loiola, R., Martin, L., Kusters, D. H., ... & Solito, E. (2018). Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes. Diabetologia, 61(2), 482-495.

Pietrani, N. T., Ferreira, C. N., Rodrigues, K. F., Perucci, L. O., Carneiro, F. S., Bosco, A. A., ... & Gomes, K. B. (2018). Proresolving protein Annexin A1: The role in type 2 diabetes mellitus and obesity. Biomedicine & Pharmacotherapy, 103, 482-489.

Lima, K. M., Vago, J. P., Caux, T. R., Negreiros-Lima, G. L., Sugimoto, M. A., Tavares, L. P., ... & Sousa, L. P. (2017). The resolution of acute inflammation induced by cyclic AMP is dependent on annexin A1. Journal of Biological Chemistry, 292(33), 13758-13773.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

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