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APOA1 Matched Antibody Pair (092) (APMAB-092LY)

This antibody pair set can be used for detecting and quantifying protein level of human APOA1.
See all APOA1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-APOA1 polyclonal antibody, 100 ug
Detection Antibody
Anti-APOA1 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]
Alternative Names
Apolipoprotein A1; Apolipoprotein A-I; Apo-AI; Apo(A); ApoA-I;
Entrez Gene ID
335
UniProt ID
P02647

Saraf, S. L., Zhang, X., Shah, B. N., Raslan, R., Tayo, B. O., Lash, J. P., ... & Gordeuk, V. R. (2021). Engulfment and cell motility 1 (ELMO1) and apolipoprotein A1 (APOA1) as candidate genes for sickle cell nephropathy. British Journal of Haematology, 193(3), 628-632.

Ducroux, C., Desilles, J. P., Mawhin, M. A., Delbosc, S., Ho-Tin-Noé, B., Ollivier, V., ... & Amarenco, P. (2020). Protective effect of ApoA1 (apolipoprotein a1)-milano in a rat model of large vessel occlusion stroke. Stroke, 51(6), 1886-1890.

Yiu, J. H., Chan, K. S., Cheung, J., Li, J., Liu, Y., Wang, Y., ... & Woo, C. W. (2020). Gut microbiota-associated activation of TLR5 induces apolipoprotein A1 production in the liver. Circulation research, 127(10), 1236-1252.

Melhem, H., Kallol, S., Huang, X., Lüthi, M., Ontsouka, C. E., Keogh, A., ... & Albrecht, C. (2019). Placental secretion of apolipoprotein A1 and E: the anti-atherogenic impact of the placenta. Scientific reports, 9(1), 1-12.

Liu, J. X., Yuan, Q., Min, Y. L., He, Y., Xu, Q. H., Li, B., ... & Shao, Y. (2019). Apolipoprotein A1 and B as risk factors for development of intraocular metastasis in patients with breast cancer. Cancer management and research, 11, 2881.

Chen, B. D., Chen, X. C., Yang, Y. N., Gao, X. M., Ma, X., Huang, Y., ... & Ma, Y. T. (2019). Apolipoprotein A1 is associated with SYNTAX score in patients with a non-ST segment elevation myocardial infarction. Lipids in health and disease, 18(1), 1-8.

Lin, C. Y., Sheu, J. J., Tsai, I. S., Wang, S. T., Yang, L. Y., Hsu, I. U., ... & Lin, Y. F. (2018). Elevated IgM against Nε-(Carboxyethyl) lysine-modified Apolipoprotein A1 peptide 141–147 in Taiwanese with Alzheimer's disease. Clinical biochemistry, 56, 75-82.

Ma, M. Z., Yuan, S. Q., Chen, Y. M., & Zhou, Z. W. (2018). Preoperative apolipoprotein B/apolipoprotein A1 ratio: a novel prognostic factor for gastric cancer. OncoTargets and therapy, 11, 2169.

Sirniö, P., Väyrynen, J. P., Klintrup, K., Mäkelä, J., Mäkinen, M. J., Karttunen, T. J., & Tuomisto, A. (2017). Decreased serum apolipoprotein A1 levels are associated with poor survival and systemic inflammatory response in colorectal cancer. Scientific reports, 7(1), 1-8.

Slot, R. E., Van Harten, A. C., Kester, M. I., Jongbloed, W., Bouwman, F. H., Teunissen, C. E., ... & Van Der Flier, W. M. (2017). Apolipoprotein A1 in cerebrospinal fluid and plasma and progression to Alzheimer’s disease in non-demented elderly. Journal of Alzheimer's Disease, 56(2), 687-697.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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