ATP6AP1 Matched Antibody Pair (117) (APMAB-117LY)

Name: ATP6AP1 Matched Antibody Pair (117)
SKU: APMAB-117LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-ATP6AP1 monoclonal, IgG1 antibody, 100 ug

Detection Antibody

Anti-ATP6AP1 Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]

Alternative Names

ATPase H+ Transporting Accessory Protein 1; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump), Subunit 1; ATPase, H+ Transporting, Lysosomal Accessory Protein 1; Vacuolar Proton Pump Subunit S1; V-ATPase S1 Accessory Protein; V-ATPase Ac45 Subunit; V-ATPase Subunit S1; Protein XAP-3; ATP6IP1; ATP6S1;

Entrez Gene ID

537

UniProt ID

Q15904

More Infomation

References

Wang, J., Liu, Y., & Zhang, S. (2021). Prognostic and immunological value of ATP6AP1 in breast cancer: implications for SARS-CoV-2. Aging (Albany NY), 13(13), 16904.

Tvina, A., Thomsen, A., & Palatnik, A. (2020). Prenatal and postnatal phenotype of a pathologic variant in the ATP6AP1 gene. European journal of medical genetics, 63(6), 103881.

Ondruskova, N., Honzik, T., Vondrackova, A., Stranecky, V., Tesarova, M., Zeman, J., & Hansikova, H. (2020). Severe phenotype of ATP6AP1‐CDG in two siblings with a novel mutation leading to a differential tissue‐specific ATP6AP1 protein pattern, cellular oxidative stress and hepatic copper accumulation. Journal of inherited metabolic disease, 43(4), 694-700.

Dimitrov, B., Himmelreich, N., Ederveen, A. L. H., Lüchtenborg, C., Okun, J. G., Breuer, M., ... & Thiel, C. (2018). Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolomics as additional symptoms in a new patient with ATP6AP1-CDG. Molecular genetics and metabolism, 123(3), 364-374.

Dimitrov, B. (2017). Klinische, molekularbiologische und biochemische Charakterisierung eines neuen Patientendefekts im „ATPase H+-transporting accessory protein 1 “(ATP6AP1)-Gen (Doctoral dissertation).

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-ATP6AP1 Recombinant Antibody (85)

Mouse Anti-ATP6AP1 Recombinant Antibody (3B11)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Second antibody and isotype control

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