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BMPR1B Matched Antibody Pair (142) (APMAB-142LY)

This antibody pair set can be used for detecting and quantifying protein level of human BMPR1B.
See all BMPR1B antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-BMPR1B monoclonal, IgG1 antibody, 100 ug
Detection Antibody
Anti-BMPR1B Biotinylated mouse monoclonal, IgG1 antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Alternative Names
Bone Morphogenetic Protein Receptor Type 1B; Bone Morphogenetic Protein Receptor, Type IB; BMP Type-1B Receptor; EC 2.7.11.30; BMPR-1B; Bone Morphogenetic Protein Receptor Type-1B; Serine/Threonine Receptor Kinase; Activin Receptor-Like Kinase 6; CDw293 Antigen;
Entrez Gene ID
658
UniProt ID
O00238

Chinedu, O., Tonassé, W. V., Albuquerque, D. M., de Farias Domingos, I., da Silva Araújo, A., Bezerra, M. A. C., ... & Dos Santos, M. N. N. (2021). Polymorphisms in the heme oxygenase-1 and bone morphogenetic protein receptor type 1b genes and estimated glomerular filtration rate in Brazilian sickle cell anemia patients. Hematology, Transfusion and Cell Therapy, 43(2), 165-170.

ÃelikeloÄlu, K., Tekerli, M., ErdoÄan, M., Koçak, S., Hacan, Ö., & Bozkurt, Z. (2021). An investigation of the effects of BMPR1B, BMP15, and GDF9 genes on litter size in Ramlıç and DaÄlıç sheep. Archives Animal Breeding, 64(1), 223-223.

Pourali Dogaheh, S., Mirhoseini, S. Z., Tufarelli, V., Hossein-Zadeh, N. G., Badbarin, S., Colonna, M. A., ... & Selvaggi, M. (2020). Investigating the Polymorphism of Bone Morphogenetic Protein Receptor-1B (BMPR1B) Gene in Markhoz Goat Breed. Animals, 10(9), 1582.

Alshangiti, A. M., Wyatt, S. L., McCarthy, E., Collins, L. M., Hegarty, S. V., Sullivan, A. M., & O’Keeffe, G. W. (2020). Association of distinct type 1 bone morphogenetic protein receptors with different molecular pathways and survival outcomes in neuroblastoma. Neuronal signaling, 4(1), NS20200006.

Wu, Y. J., Lee, Y. N., Wu, T. W., Chou, C. L., & Wang, L. Y. (2019). Common Genetic Variants on Bone Morphogenetic Protein Receptor Type IB (BMPR1B) Gene Are Predictive for Carotid Intima-Media Thickness. Circulation Journal, 83(4), 749-756.

Yao, Y., Reheman, A., Xu, Y., & Li, Q. (2019). miR-125b contributes to ovarian granulosa cell apoptosis through targeting BMPR1B, a major gene for sheep prolificacy. Reproductive Sciences, 26(2), 295-305.

Yao, Y., Niu, J., Sizhu, S., Li, B., Chen, Y., Li, R., ... & Xu, Y. (2018). microRNA-125b regulates apoptosis by targeting bone morphogenetic protein receptor 1B in yak granulosa cells. DNA and cell biology, 37(11), 878-887.

Zhou, S., Yu, H., Zhao, X., Cai, B., Ding, Q., Huang, Y., ... & Wang, X. (2018). Generation of gene-edited sheep with a defined Booroola fecundity gene (FecBB) mutation in bone morphogenetic protein receptor type 1B (BMPR1B) via clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) 9. Reproduction, Fertility and Development, 30(12), 1616-1621.

Kumari, R., Dayal, S., Kumar, S., Chandran, P. C., & Dey, A. (2017). Genetic polymorphism of bone morphogenetic protein receptor type-1 (BMPR1B) gene in crossbred does of Bihar. Indian Journal of Animal Sciences, 87, 4.

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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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