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CCDC6 Matched Antibody Pair (195) (APMAB-195LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-CCDC6 polyclonal antibody, 100 ug
Detection Antibody
Anti-CCDC6 Mouse monoclonal, IgG1 antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
CCDC6 (Coiled-Coil Domain Containing 6) is a Protein Coding gene. Diseases associated with CCDC6 include Thyroid Cancer, Nonmedullary, 1 and Differentiated Thyroid Carcinoma. Among its related pathways are Mesodermal Commitment Pathway and Retinoblastoma (RB) in Cancer. Gene Ontology (GO) annotations related to this gene include SH3 domain binding and structural constituent of cytoskeleton.
Alternative Names
Coiled-Coil Domain Containing 6; Papillary Thyroid Carcinoma-Encoded Protein; D10S170; TST1; DNA Segment, Single Copy, Probe PH4 (Transforming Sequence, Thyroid-1; DNA Segment On Chromosome 10 (Unique) 170;
Entrez Gene ID
8030
UniProt ID
Q16204
More Infomation

Morra, F., Merolla, F., Marino, F. Z., Catalano, R., Franco, R., Chieffi, P., & Celetti, A. (2021). The tumour suppressor CCDC6 is involved in ROS tolerance and neoplastic transformation by evading ferroptosis. Heliyon, e08399.

Jin, D., Huang, K., Peng, L., Xu, P., Dang, Y., Yang, J., ... & Zhang, G. (2021). Circular RNA circDNA2 upregulates CCDC6 expression to promote the progression and unfavorable prognosis of gastric cancer via miR-149-5p suppression. Molecular Therapy-Nucleic Acids.

Liu, Y., Li, K., Zhu, W. B., Zhang, H., Huang, W. T., Liu, X. C., ... & Hu, C. (2021). Suppression of CCDC6 sensitizes tumor to oncolytic virus M1. Neoplasia, 23(1), 158-168.

Tang, Y., Yang, J., Wang, Y., Tang, Z., Liu, S., & Tang, Y. (2020). MiR-19b-3p facilitates the proliferation and epithelial-mesenchymal transition, and inhibits the apoptosis of intrahepatic cholangiocarcinoma by suppressing coiled-coil domain containing 6. Archives of biochemistry and biophysics, 686, 108367.

Laxmi, A., Gupta, P., & Gupta, J. (2019). CCDC6, a gene product in fusion with different protoncogenes, as a potential chemotherapeutic target. Cancer Biomarkers, 24(4), 383-393.

Jia, M., Shi, Y., Li, Z., Lu, X., & Wang, J. (2019). MicroRNA-146b-5p as an oncomiR promotes papillary thyroid carcinoma development by targeting CCDC6. Cancer letters, 443, 145-156.

Morra, F., Merolla, F., D’Abbiero, D., Ilardi, G., Campione, S., Monaco, R., ... & Celetti, A. (2019). Analysis of CCDC6 as a novel biomarker for the clinical use of PARP1 inhibitors in malignant pleural mesothelioma. Lung Cancer, 135, 56-65.

Cerrato, A., Merolla, F., Morra, F., & Celetti, A. (2018). CCDC6: the identity of a protein known to be partner in fusion. International journal of cancer, 142(7), 1300-1308.

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For research use only. Not intended for any clinical use.

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