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CCL2 Matched Antibody Pair (196) (APMAB-196LY)

This antibody pair set can be used for detecting and quantifying protein level of human CCL2.
See all CCL2 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-CCL2 monoclonal antibody, 100 ug
Detection Antibody
Anti-CCL2 Biotinylated mouse monoclonal, IgG2a antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
CCL2 (C-C Motif Chemokine Ligand 2) is a Protein Coding gene, and is affiliated with the lncRNA class. Diseases associated with CCL2 include Neural Tube Defects and Human Immunodeficiency Virus Type 1. Among its related pathways are Ectoderm Differentiation and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include protein kinase activity and heparin binding. An important paralog of this gene is CCL7.
Alternative Names
C-C Motif Chemokine Ligand 2; Monocyte Chemotactic And Activating Factor; Monocyte Secretory Protein JE; Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1, Homologous To Mouse Sig-Je); Small Inducible Cytokine Subfamily A (Cys-Cys), Member 2; Monocyte Chemoattractant Protein-1; Chemokine (C-C Motif) Ligand 2; Monocyte Chemotactic Protein 1; Small-Inducible Cytokine A2; SCYA2; MCP-1;
Entrez Gene ID
6347

Dommel, S., & Blüher, M. (2021). Does CC Motif Chemokine Ligand 2 (CCL2) Link Obesity to a Pro-Inflammatory State?. International Journal of Molecular Sciences, 22(3), 1500.

Schettini, I. V. G., Faria, D. V., Nogueira, L. S., Otoni, A., Silva, A. C. S., & Rios, D. R. A. (2021). Renin angiotensin system molecules and chemokine (CC motif) ligand 2 (CCL2) in chronic kidney disease patients. Brazilian Journal of Nephrology.

Li, M., Chen, Y., Zhang, Y., Li, D., & Liu, J. (2020). Correlation between monocyte chemoattractant protein-1/chemokine (CC motif) ligand 2 and coronary plaque characteristics. Experimental Biology and Medicine, 245(15), 1335-1343.

Iwamoto, H., Izumi, K., & Mizokami, A. (2020). Is the CC Motif Ligand 2–CC Chemokine Receptor 2 Axis a Promising Target for Cancer Therapy and Diagnosis?. International Journal of Molecular Sciences, 21(23), 9328.

Hernández-Aguilera, A., Fibla, M., Cabré, N., Luciano-Mateo, F., Camps, J., Fernández-Arroyo, S., ... & Joven, J. (2020). Chemokine (CC motif) ligand 2 and coronary artery disease: tissue expression of functional and atypical receptors. Cytokine, 126, 154923.

Luciano-Mateo, F., Cabré, N., Baiges-Gaya, G., Fernández-Arroyo, S., Hernández-Aguilera, A., Rodríguez-Tomàs, E. E., ... & Joven, J. (2020). Systemic overexpression of CC motif chemokine ligand 2 promotes metabolic dysregulation and premature death in mice with accelerated aging. Aging (Albany NY), 12(20), 20001.

Li, L., Lou, W., Li, H., & Zhu, Y. (2020). Upregulated CC motif chemokine ligand 2 promotes ischemic stroke via chemokine signaling pathway. Annals of Vascular Surgery, 68, 476-486.

Kimura, A., Yoshikura, N., Hayashi, Y., & Inuzuka, T. (2018). Cerebrospinal fluid CC motif chemokine ligand 2 correlates with brain atrophy and cognitive impairment in Alzheimer’s disease. Journal of Alzheimer's Disease, 61(2), 581-588.

Yoshida, H., Imaizumi, T., Matsumiya, T., Seya, K., Kawaguchi, S., & Tanaka, H. (2018). Gnetin C suppresses double-stranded RNA-induced CC motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway. Biomedical Research, 39(5), 231-240.

Lai, C., Wang, K., Zhao, Z., Zhang, L., Gu, H., Yang, P., & Wang, X. (2017). CC motif chemokine ligand 2 (CCL2) mediates acute lung injury induced by lethal influenza H7N9 virus. Frontiers in microbiology, 8, 587.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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