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CD274 Matched Antibody Pair (214) (APMAB-214LY)

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-CD274 monoclonal, IgG2b antibody, 100 ug

Detection Antibody

Anti-CD274 Biotinylated mouse monoclonal, IgG2b antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Alternative Names

CD274 Molecule; CD274 Antigen; B7 Homolog 1; Programmed Cell Death 1 Ligand 1; PDCD1 Ligand 1; PDCD1LG1; PDCD1L1;

Entrez Gene ID

UniProt ID

More Infomation

Verocq, C., Decaestecker, C., Rocq, L., De Clercq, S., Verrellen, A., Mekinda, Z., ... & D'haene, N. (2020). The daily practice reality of PD‑L1 (CD274) evaluation in non‑small cell lung cancer: A retrospective study. Oncology letters, 19(5), 3400-3410.

Riemann, D., Schütte, W., Turzer, S., Seliger, B., & Möller, M. (2020). High PD-L1/CD274 Expression of Monocytes and Blood Dendritic Cells Is a Risk Factor in Lung Cancer Patients Undergoing Treatment with PD1 Inhibitor Therapy. Cancers, 12(10), 2966.

Kim, J. Y., Lee, K. H., Kang, J., Borcoman, E., Saada-Bouzid, E., Kronbichler, A., ... & Gamerith, G. (2019). Hyperprogressive disease during anti-PD-1 (PDCD1)/PD-L1 (CD274) therapy: a systematic review and meta-analysis. Cancers, 11(11), 1699.

Fabrizio, F. P., Trombetta, D., Rossi, A., Sparaneo, A., Castellana, S., & Muscarella, L. A. (2018). Gene code CD274/PD-L1: from molecular basis toward cancer immunotherapy. Therapeutic advances in medical oncology, 10, 1758835918815598.

Huang, C. Y., Chiang, S. F., Ke, T. W., Chen, T. W., You, Y. S., Chen, W. T. L., & Chao, K. C. (2018). Clinical significance of programmed death 1 ligand-1 (CD274/PD-L1) and intra-tumoral CD8+ T-cell infiltration in stage II–III colorectal cancer. Scientific reports, 8(1), 1-10.

Clavé, S., Pijuan, L., Casadevall, D., Taus, Á., Gimeno, J., Hernández‐Llodrà, S., ... & Salido, M. (2018). CD 274 (PDL 1) and JAK 2 genomic amplifications in pulmonary squamous‐cell and adenocarcinoma patients. Histopathology, 72(2), 259-269.

Yang, L., Cai, Y., Zhang, D., Sun, J., Xu, C., Zhao, W., ... & Pan, C. (2018). miR-195/miR-497 regulate CD274 expression of immune regulatory ligands in triple-negative breast cancer. Journal of breast cancer, 21(4), 371-381.

Sun, J., Lian, M., Ma, H., Wang, R., Ma, Z., Wang, H., ... & Fang, J. (2018). Competing endogenous RNA network analysis of CD274, IL‑10 and FOXP3 co‑expression in laryngeal squamous cell carcinoma. Molecular medicine reports, 17(3), 3859-3869.

Lee, S. J., Jun, S. Y., Lee, I. H., Kang, B. W., Park, S. Y., Kim, H. J., ... & Kim, J. G. (2018). CD274, LAG3, and IDO1 expressions in tumor-infiltrating immune cells as prognostic biomarker for patients with MSI-high colon cancer. Journal of cancer research and clinical oncology, 144(6), 1005-1014.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus, Rhesus Recombinant CD274 protein, Fc Tag (CAT#: V2LY-0526-LY27)

Cynomolgus, Rhesus Recombinant CD274 protein, His Tag (CAT#: V2LY-0526-LY28)

Cynomolgus, Rhesus Recombinant CD274 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY29)

Canine Recombinant CD274 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY1307)

Canine Recombinant CD274 protein, ECD, hFc Tag-1 (CAT#: V2LY-0526-LY1308)

Canine Recombinant CD274 protein, ECD, His Tag (CAT#: V2LY-0526-LY1309)

Canine Recombinant CD274 protein, ECD, His Tag-1 (CAT#: V2LY-0526-LY1310)

Canine Recombinant CD274 protein, Biotin Conjugated, hFc Tag (CAT#: V2LY-0526-LY1311)

Cynomolgus, Rhesus Recombinant CD274 protein, Biotin Conjugated, hFc & AVI Tag (CAT#: V2LY-0526-LY1733)

Cynomolgus, Rhesus Recombinant CD274 protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY1734)

Related Products

Human Recombinant CD274 protein, ECD, hFc Tag-1 (CAT#: V2LY-0526-LY6081)

Feline Recombinant CD274 protein, His Tag (CAT#: V2LY-0526-LY1792)

Mouse Recombinant CD274 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY8762)

Mouse Anti-CD274 Recombinant Antibody (CBFYC-1193) (CAT#: CBMAB-C1251-FY)

Human Recombinant CD274 protein, ECD, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY6083)

Human Recombinant CD274 protein, ECD, His Tag (CAT#: V2LY-0526-LY6085)

Mouse Anti-CD274 Recombinant Antibody (1C10) (CAT#: CBMAB-C3701-LY)

Mouse Anti-CD274 Recombinant Antibody (CBT2951) (CAT#: V2LY-0625-LY1093)

Human Recombinant CD274 proteinECD (CAT#: V2LY-0526-LY6077)

Canine Recombinant CD274 protein, Biotin Conjugated, hFc Tag (CAT#: V2LY-0526-LY1311)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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