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CD28 Matched Antibody Pair (216) (APMAB-216LY)

This antibody pair set can be used for detecting and quantifying protein level of human CD28.
See all CD28 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-CD28 monoclonal antibody, 100 ug
Detection Antibody
Anti-CD28 Biotinylated mouse monoclonal, IgG2b antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
CD28 (CD28 Molecule) is a Protein Coding gene. Diseases associated with CD28 include Mycosis Fungoides and Sezary's Disease. Among its related pathways are Th2 Differentiation Pathway and RET signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding and SH3/SH2 adaptor activity. An important paralog of this gene is CTLA4.
Alternative Names
CD28 Molecule; CD28 Antigen; Tp44; T-Cell-Specific Surface Glycoprotein CD28; T-Cell-Specific Surface Glycoprotein; CD28 Antigen (Tp44);
Entrez Gene ID
UniProt ID

Matundan, H. H., Jaggi, U., Yu, J., Akbari, O., & Ghiasi, H. (2021). Absence of CD28-CTLA4-PD-L1 Costimulatory Molecules Reduces Herpes Simplex Virus 1 Reactivation. Mbio, 12(4), e01176-21.

Nagai, S., & Azuma, M. (2019). The CD28–B7 family of co-signaling molecules. Co-signal Molecules in T Cell Activation, 25-51.

Huff, W. X., Kwon, J. H., Henriquez, M., Fetcko, K., & Dey, M. (2019). The evolving role of CD8+ CD28− immunosenescent T cells in cancer immunology. International journal of molecular sciences, 20(11), 2810.

Hosoe, Y., Numoto, N., Inaba, S., Ogawa, S., Morii, H., Abe, R., ... & Oda, M. (2019). Structural and functional properties of Grb2 SH2 dimer in CD28 binding. Biophysics and physicobiology, 16, 80-88.

Siokis, A., Robert, P. A., Demetriou, P., Dustin, M. L., & Meyer-Hermann, M. (2018). F-actin-driven CD28-CD80 localization in the immune synapse. Cell reports, 24(5), 1151-1162.

Huang, Y., Wang, Z., Zheng, Q., Tang, J., Cai, J., Lu, Y., & Jian, J. (2018). Conservation of structural and interactional features of CD28 and CD80/86 molecules from Nile tilapia (Oreochromis niloticus). Fish & shellfish immunology, 72, 95-103.

Xia, F., Qian, C. R., Xun, Z., Hamon, Y., Sartre, A. M., Formisano, A., ... & He, H. T. (2018). TCR and CD28 concomitant stimulation elicits a distinctive calcium response in naive T cells. Frontiers in immunology, 9, 2864.

Porciello, N., Grazioli, P., Campese, A. F., Kunkl, M., Caristi, S., Mastrogiovanni, M., ... & Tuosto, L. (2018). A non-conserved amino acid variant regulates differential signalling between human and mouse CD28. Nature communications, 9(1), 1-16.

Yang, W., Pan, W., Chen, S., Trendel, N., Jiang, S., Xiao, F., ... & Xu, C. (2017). Dynamic regulation of CD28 conformation and signaling by charged lipids and ions. Nature structural & molecular biology, 24(12), 1081-1092.

Zumerle, S., Molon, B., & Viola, A. (2017). Membrane rafts in T cell activation: a spotlight on CD28 costimulation. Frontiers in immunology, 8, 1467.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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