CTTN Matched Antibody Pair (319) (APMAB-319LY)

This antibody pair set can be used for detecting and quantifying protein level of human CTTN.
See all CTTN antibodies

Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-CTTN polyclonal antibody, 100 ug

Detection Antibody

Anti-CTTN Mouse polyclonal antibody, 40 ul

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

CTTN (Cortactin) is a Protein Coding gene. Diseases associated with CTTN include Ethmoid Sinus Adenocarcinoma and Ethmoid Sinus Cancer. Among its related pathways are N-cadherin signaling events and Development Slit-Robo signaling. Gene Ontology (GO) annotations related to this gene include profilin binding. An important paralog of this gene is HCLS1.

Alternative Names

Cortactin; Ems1 Sequence (Mammary Tumor And Squamous Cell Carcinoma-Associated (P80/85 Src Substrate); Oncogene EMS1; Amplaxin; EMS1; Src Substrate Cortactin; 1110020L01Rik;

Entrez Gene ID

2017

UniProt ID

Q14247

References

Belvitch, P., Casanova, N., Sun, X., Camp, S. M., Sammani, S., Brown, M. E., ... & Dudek, S. M. (2022). A cortactin CTTN coding SNP contributes to lung vascular permeability and inflammatory disease severity in African descent subjects. Translational Research.

Zhao, Y., Lei, Y., He, S. W., Li, Y. Q., Wang, Y. Q., Hong, X. H., ... & Tang, L. L. (2020). Hypermethylation of UCHL1 promotes metastasis of nasopharyngeal carcinoma by suppressing degradation of cortactin (CTTN). Cells, 9(3), 559.

Ramos‐García, P., González‐Moles, M. Á., Ayen, A., González‐Ruiz, L., Ruiz‐Ávila, I., & Gil‐Montoya, J. A. (2019). Prognostic and clinicopathological significance of CTTN/cortactin alterations in head and neck squamous cell carcinoma: systematic review and meta‐analysis. Head & Neck, 41(6), 1963-1978.

Ramos‐García, P., González‐Moles, M. Á., González‐Ruiz, L., Ayén, Á., Ruiz‐Ávila, I., Navarro‐Triviño, F. J., & Gil‐Montoya, J. A. (2019). An update of knowledge on cortactin as a metastatic driver and potential therapeutic target in oral squamous cell carcinoma. Oral Diseases, 25(4), 949-971.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

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Mouse Anti-CTTN Recombinant Antibody (0-T-21)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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