Cynomolgus Recombinant THPO protein, His Tag (V2LY-0526-LY1661)

Name: Cynomolgus Recombinant THPO protein, His Tag
SKU: V2LY-0526-LY1661
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Cynomolgus

Tag

His Tag

Protein Construction

This product is Cynomolgus Recombinant THPO protein, His Tag consist of Amino Acid: 1-353 and predicts a molecular mass of 36.8 kDa.

Molecule Mass

36.8 kDa

Sequence

Amino Acid: 1-353

Species

Cynomolgus

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>86% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile Sodium phosphate, NaCl, Imidazole, PMSF, DTT, Glycerol

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Thrombopoietin

Function

Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

Biological Process

Biological Process cell population proliferationSource:InterPro
Biological Process cellular response to lipopolysaccharideSource:Ensembl
Biological Process megakaryocyte developmentSource:ARUK-UCL1 Publication
Biological Process megakaryocyte differentiationSource:UniProtKB1 Publication
Biological Process positive regulation of cell population proliferationSource:ARUK-UCL1 Publication
Biological Process positive regulation of ERK1 and ERK2 cascadeSource:UniProtKB
Biological Process positive regulation of hematopoietic stem cell proliferationSource:MGI1 Publication
Biological Process positive regulation of MAPK cascadeSource:ARUK-UCL1 Publication
Biological Process positive regulation of megakaryocyte differentiationSource:UniProtKB
Biological Process positive regulation of protein kinase B signalingSource:ARUK-UCL1 Publication
Biological Process positive regulation of protein phosphorylationSource:UniProtKB
Biological Process receptor signaling pathway via STATSource:ARUK-UCL1 Publication
Biological Process thrombopoietin-mediated signaling pathwaySource:ARUK-UCL1 Publication

Cellular Location

Secreted

Involvement in disease

Thrombocythemia 1 (THCYT1):
A myeloproliferative disorder characterized by excessive platelet production, resulting in increased numbers of circulating platelets. It can be associated with spontaneous hemorrhages and thrombotic episodes.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rat Thpo ELISA Kit (CAT#: V2LY-0626-LY1090)

Human THPO ELISA Kit (CAT#: V2LY-0626-LY1334)

Mouse Thpo ELISA Kit (CAT#: V2LY-0626-LY388)

Related Products

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Mouse Thpo ELISA Kit (CAT#: V2LY-0626-LY388)

Rat Thpo ELISA Kit (CAT#: V2LY-0626-LY1090)

Mouse Anti-THPO Recombinant Antibody (CBYJT-3025) (CAT#: CBMAB-T2275-YJ)

Rabbit Anti-Thpo Recombinant Antibody (CBYJT-3028) (CAT#: CBMAB-T2278-YJ)

Mouse Anti-THPO Recombinant Antibody (CBT2869) (CAT#: V2LY-0625-LY2776)

Mouse Anti-THPO Recombinant Antibody (CBYJT-3026) (CAT#: CBMAB-T2276-YJ)

Rat Anti-Thpo Recombinant Antibody (CBYJT-3027) (CAT#: CBMAB-T2277-YJ)

Mouse Anti-THPO Recombinant Antibody (CBYJT-3019) (CAT#: CBMAB-T2269-YJ)

Human THPO ELISA Kit (CAT#: V2LY-0626-LY1334)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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