Cynomolgus Recombinant XCL1 protein, His Tag (V2LY-0526-LY1599)

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Basic Information

Expressed Host
Baculovirus-Insect Cells
Protein Species
Cynomolgus
Tag
His Tag
Protein Construction
This product is Cynomolgus Recombinant XCL1 protein, His Tag consist of Amino Acid: 1-114 and predicts a molecular mass of 11.6 kDa.
Molecule Mass
11.6 kDa
Sequence
Amino Acid: 1-114
Species
Cynomolgus

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>90% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
chemokine (C motif) ligand 1
Function
Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Biological Process
Biological Process antimicrobial humoral immune response mediated by antimicrobial peptide Source:UniProtKB
Biological Process cell-cell signaling Source:BHF-UCL1 Publication
Biological Process cellular response to interleukin-1 Source:GO_Central1 Publication
Biological Process cellular response to interleukin-4 Source:BHF-UCL
Biological Process cellular response to transforming growth factor beta stimulus Source:BHF-UCL
Biological Process cellular response to tumor necrosis factor Source:GO_Central1 Publication
Biological Process cellular response to type II interferon Source:GO_Central1 Publication
Biological Process chemokine-mediated signaling pathway Source:GO_Central1 Publication
Biological Process G protein-coupled receptor signaling pathway Source:GO_Central1 Publication
Biological Process inflammatory response Source:GO_Central1 Publication
Biological Process killing of cells of another organism Source:UniProtKB
Biological Process lymphocyte chemotaxis Source:GO_Central1 Publication
Biological Process mature natural killer cell chemotaxis Source:BHF-UCL1 Publication
Biological Process monocyte chemotaxis Source:GO_Central1 Publication
Biological Process negative regulation of CD4-positive, alpha-beta T cell proliferation Source:BHF-UCL1 Publication
Biological Process negative regulation of DNA-binding transcription factor activity Source:BHF-UCL1 Publication
Biological Process negative regulation of DNA-templated transcription Source:BHF-UCL1 Publication
Biological Process negative regulation of interleukin-2 production Source:BHF-UCL1 Publication
Biological Process negative regulation of T cell cytokine production Source:BHF-UCL1 Publication
Biological Process negative regulation of T-helper 1 cell activation Source:BHF-UCL1 Publication
Biological Process negative regulation of T-helper 1 type immune response Source:BHF-UCL1 Publication
Biological Process negative regulation of type II interferon production Source:BHF-UCL1 Publication
Biological Process neutrophil chemotaxis Source:GO_Central1 Publication
Biological Process positive regulation of B cell chemotaxis Source:BHF-UCL
Biological Process positive regulation of CD4-positive, alpha-beta T cell proliferation Source:BHF-UCL
Biological Process positive regulation of CD8-positive, alpha-beta T cell proliferation Source:BHF-UCL1 Publication
Biological Process positive regulation of ERK1 and ERK2 cascade Source:GO_Central1 Publication
Biological Process positive regulation of granzyme A production Source:BHF-UCL1 Publication
Biological Process positive regulation of granzyme B production Source:BHF-UCL1 Publication
Biological Process positive regulation of GTPase activity Source:GO_Central1 Publication
Biological Process positive regulation of immunoglobulin production in mucosal tissue Source:BHF-UCL
Biological Process positive regulation of interleukin-10 production Source:BHF-UCL1 Publication
Biological Process positive regulation of leukocyte chemotaxis Source:BHF-UCL
Biological Process positive regulation of natural killer cell chemotaxis Source:BHF-UCL1 Publication
Biological Process positive regulation of neutrophil chemotaxis Source:BHF-UCL
Biological Process positive regulation of release of sequestered calcium ion into cytosol Source:BHF-UCL1 Publication
Biological Process positive regulation of T cell chemotaxis Source:BHF-UCL1 Publication
Biological Process positive regulation of T cell cytokine production Source:BHF-UCL
Biological Process positive regulation of T cell mediated cytotoxicity Source:BHF-UCL1 Publication
Biological Process positive regulation of T-helper 1 cell cytokine production Source:BHF-UCL
Biological Process positive regulation of T-helper 2 cell cytokine production Source:BHF-UCL
Biological Process positive regulation of thymocyte migration Source:BHF-UCL
Biological Process positive regulation of transforming growth factor beta production Source:BHF-UCL1 Publication
Biological Process regulation of inflammatory response Source:BHF-UCL1 Publication
Biological Process release of sequestered calcium ion into cytosol Source:BHF-UCL
Biological Process response to virus Source:BHF-UCL1 Publication
Biological Process signal transduction Source:BHF-UCL1 Publication
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

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