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F11R Matched Antibody Pair (394) (APMAB-394LY)

This antibody pair set can be used for detecting and quantifying protein level of human F11R.
See all F11R antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-F11R polyclonal antibody, 100 ug
Detection Antibody
Anti-F11R Mouse monoclonal, IgG1 antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
Alternative Names
F11 Receptor; Junctional Adhesion Molecule 1; Platelet Adhesion Molecule 1; Platelet F11 Receptor; PAM-1; JAM1; JCAM; Junctional Adhesion Molecule A;
Entrez Gene ID
UniProt ID

Czubak-Prowizor, K., Babinska, A., & Swiatkowska, M. (2022). The F11 receptor (F11R)/junctional adhesion molecule-A (JAM-A)(F11R/JAM-A) in cancer progression. Molecular and Cellular Biochemistry, 477(1), 79-98.

Li, Y., Peng, L., Cao, X., Yang, K., Wang, Z., Xiao, Y., ... & Liu, H. (2022). The Long Non-Coding RNA HOXC-AS3 Promotes Glioma Progression by Sponging miR-216 to Regulate F11R Expression. Frontiers in oncology, 12, 845009-845009.

Adedayo, A., Eluwole, A., Tedla, F., Kremer, A., Khan, M., Mastrogiovanni, N., ... & Bakillah, A. (2022). Relationship between the Soluble F11 Receptor and Annexin A5 in African Americans Patients with Type-2 Diabetes Mellitus. Biomedicines, 10(8), 1818.

Guo, X., Gu, Y., Guo, C., Pei, L., & Hao, C. (2022). LINC01146/F11R facilitates growth and metastasis of prostate cancer under the regulation of TGF-β. The Journal of Steroid Biochemistry and Molecular Biology, 106193.

Tian, Y., Fopiano, K. A., Buncha, V., Lang, L., Rudic, R. D., Filosa, J. A., ... & Bagi, Z. (2022). Aging-induced impaired endothelial wall shear stress mechanosensing causes arterial remodeling via JAM-A/F11R shedding by ADAM17. GeroScience, 44(1), 349-369.

Bednarek, R., Selmi, A., Wojkowska, D., Karolczak, K., Popielarski, M., Stasiak, M., ... & Swiatkowska, M. (2020). Functional inhibition of F11 receptor (F11R/junctional adhesion molecule-A/JAM-A) activity by a F11R-derived peptide in breast cancer and its microenvironment. Breast Cancer Research and Treatment, 179(2), 325-335.

Babinska, A., Clement, C. C., Li, Y., Wzorek, J., Przygodzki, T., Talar, M., ... & Salifu, M. O. (2020). In vivo data: treatment with the F11R/JAM-A peptide 4D decreases mortality and reduces the generation of atherosclerotic plaques in ApoE-deficient mice. Data in brief, 30, 105516.

Babinska, A., Clement, C. C., Przygodzki, T., Talar, M., Li, Y., Braun, M., ... & Salifu, M. O. (2019). A peptide antagonist of F11R/JAM-A reduces plaque formation and prolongs survival in an animal model of atherosclerosis. Atherosclerosis, 284, 92-101.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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