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FASLG Matched Antibody Pair (411) (APMAB-411LY)

This antibody pair set can be used for detecting and quantifying protein level of human FASLG.
See all FASLG antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-FASLG monoclonal antibody, 100 ug
Detection Antibody
Anti-FASLG Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
Alternative Names
Fas Ligand; Fas Ligand (TNF Superfamily, Member 6); Apoptosis Antigen Ligand; Fas Antigen Ligand; CD95 Ligand; APT1LG1; TNFSF6; CD95-L; CD95L; APTL; FASL;
Entrez Gene ID
356
UniProt ID
P48023

Wang, G., Duan, P., Liu, F., & Wei, Z. (2021). Long non-coding RNA CASC7 suppresses malignant behaviors of breast cancer by regulating miR-21-5p/FASLG axis. Bioengineered, 12(2), 11555-11566.

Ji, W., Xin, Y., Zhang, L., & Liu, X. (2020). ALG2 Influences T cell apoptosis by regulating FASLG intracellular transportation. Biochemical Journal, 477(16), 3105-3121.

Zou, L., Ma, X., Wu, B., Chen, Y., Xie, D., & Peng, C. (2020). Protective effect of bone marrow mesenchymal stem cell-derived exosomes on cardiomyoblast hypoxia-reperfusion injury through the miR-149/let-7c/Faslg axis. Free Radical Research, 54(10), 722-731.

Pang, T., Du, L., Li, F., Liu, Y., Ma, X., Cao, Q., ... & Yang, P. (2020). Association of apoptosis genes in PDCD1 but not PDCD1LG2, FAS, and FASLG with pediatric idiopathic uveitis in Han Chinese. Pediatric Research, 87(4), 634-638.

de Almeida Chuffa, L. G., dos Santos Souza, J., de Mello, M. C., de Oliveira Neto, M., & Carvalho, R. F. (2020). The aging whole blood transcriptome reveals a potential role of FASLG in COVID-19. bioRxiv.

Tang, M., Pan, H., Zheng, Z., Guo, Y., Peng, J., Yang, J., ... & Zhou, Y. (2019). Prostaglandin E1 protects cardiomyocytes against hypoxia-reperfusion induced injury via the miR-21-5p/FASLG axis. Bioscience reports, 39(12).

Du, X., Hong, L., Sun, L., Sang, H., Qian, A., Li, W., ... & Li, X. (2019). miR-21 induces endothelial progenitor cells proliferation and angiogenesis via targeting FASLG and is a potential prognostic marker in deep venous thrombosis. Journal of translational medicine, 17(1), 1-13.

Chen, S., Yang, C., Sun, C., Sun, Y., Yang, Z., Cheng, S., & Zhuge, B. (2019). miR-21-5p suppressed the sensitivity of hepatocellular carcinoma cells to cisplatin by targeting FASLG. DNA and cell biology, 38(8), 865-873.

Li, Y., Sun, Y., Cai, M., Zhang, H., Gao, N., Huang, H., ... & Yao, D. (2018). Fas Ligand Gene (Faslg) plays an important role in nerve degeneration and regeneration after rat sciatic nerve injury. Frontiers in Molecular Neuroscience, 11, 210.

Blaes, J., Thomé, C. M., Pfenning, P. N., Rübmann, P., Sahm, F., Wick, A., ... & Lemke, D. (2018). Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for GlioblastomaInhibition of CD95/CD95L Signaling by APG101. Molecular Cancer Research, 16(5), 767-776.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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