FASLG Matched Antibody Pair (411) (APMAB-411LY)

Name: FASLG Matched Antibody Pair (411)
SKU: APMAB-411LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-FASLG monoclonal antibody, 100 ug

Detection Antibody

Anti-FASLG Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]

Alternative Names

Fas Ligand; Fas Ligand (TNF Superfamily, Member 6); Apoptosis Antigen Ligand; Fas Antigen Ligand; CD95 Ligand; APT1LG1; TNFSF6; CD95-L; CD95L; APTL; FASL;

Entrez Gene ID

356

UniProt ID

P48023

More Infomation

Wang, G., Duan, P., Liu, F., & Wei, Z. (2021). Long non-coding RNA CASC7 suppresses malignant behaviors of breast cancer by regulating miR-21-5p/FASLG axis. Bioengineered, 12(2), 11555-11566.

Ji, W., Xin, Y., Zhang, L., & Liu, X. (2020). ALG2 Influences T cell apoptosis by regulating FASLG intracellular transportation. Biochemical Journal, 477(16), 3105-3121.

Zou, L., Ma, X., Wu, B., Chen, Y., Xie, D., & Peng, C. (2020). Protective effect of bone marrow mesenchymal stem cell-derived exosomes on cardiomyoblast hypoxia-reperfusion injury through the miR-149/let-7c/Faslg axis. Free Radical Research, 54(10), 722-731.

Pang, T., Du, L., Li, F., Liu, Y., Ma, X., Cao, Q., ... & Yang, P. (2020). Association of apoptosis genes in PDCD1 but not PDCD1LG2, FAS, and FASLG with pediatric idiopathic uveitis in Han Chinese. Pediatric Research, 87(4), 634-638.

de Almeida Chuffa, L. G., dos Santos Souza, J., de Mello, M. C., de Oliveira Neto, M., & Carvalho, R. F. (2020). The aging whole blood transcriptome reveals a potential role of FASLG in COVID-19. bioRxiv.

Tang, M., Pan, H., Zheng, Z., Guo, Y., Peng, J., Yang, J., ... & Zhou, Y. (2019). Prostaglandin E1 protects cardiomyocytes against hypoxia-reperfusion induced injury via the miR-21-5p/FASLG axis. Bioscience reports, 39(12).

Du, X., Hong, L., Sun, L., Sang, H., Qian, A., Li, W., ... & Li, X. (2019). miR-21 induces endothelial progenitor cells proliferation and angiogenesis via targeting FASLG and is a potential prognostic marker in deep venous thrombosis. Journal of translational medicine, 17(1), 1-13.

Chen, S., Yang, C., Sun, C., Sun, Y., Yang, Z., Cheng, S., & Zhuge, B. (2019). miR-21-5p suppressed the sensitivity of hepatocellular carcinoma cells to cisplatin by targeting FASLG. DNA and cell biology, 38(8), 865-873.

Li, Y., Sun, Y., Cai, M., Zhang, H., Gao, N., Huang, H., ... & Yao, D. (2018). Fas Ligand Gene (Faslg) plays an important role in nerve degeneration and regeneration after rat sciatic nerve injury. Frontiers in Molecular Neuroscience, 11, 210.

Blaes, J., Thomé, C. M., Pfenning, P. N., Rübmann, P., Sahm, F., Wick, A., ... & Lemke, D. (2018). Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for GlioblastomaInhibition of CD95/CD95L Signaling by APG101. Molecular Cancer Research, 16(5), 767-776.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rat FASLG ELISA Kit (CAT#: V2LY-0626-LY567)

Human Recombinant FASLG protein, His Tag (CAT#: V2LY-0526-LY4025)

Human Recombinant FASLG protein, ECD, His Tag (CAT#: V2LY-0526-LY4026)

Human Recombinant FASLG protein, hFc Tag (CAT#: V2LY-0526-LY4027)

Mouse Recombinant FASLG protein, His Tag (CAT#: V2LY-0526-LY8298)

Related Products

Rat FASLG ELISA Kit (CAT#: V2LY-0626-LY567)

Rabbit Anti-FASLG Recombinant Antibody (CP0684) (CAT#: V2LY-0925-LY205)

Mouse Anti-FASLG Recombinant Antibody (5F4) (CAT#: CBMAB-C3459-CN)

Mouse Anti-FASLG Recombinant Antibody (CBXF-0332) (CAT#: V2LY-0925-LY158)

Armenian Hamster Anti-FASLG Recombinant Antibody (CBYJT-1279) (CAT#: CBMAB-T0294-YJ)

Human Recombinant FASLG protein, ECD, His Tag (CAT#: V2LY-0526-LY4026)

Mouse Anti-FASLG Recombinant Antibody (CBXF-1387) (CAT#: V2LY-0925-LY125)

Human Recombinant FASLG protein, hFc Tag (CAT#: V2LY-0526-LY4027)

Rat Anti-FASLG Recombinant Antibody (CBXF-0331) (CAT#: CBMAB-F2209-CQ)

Human Recombinant FASLG protein, His Tag (CAT#: V2LY-0526-LY4025)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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