GSDMD Matched Antibody Pair (504) (APMAB-504LY)

Xie, W. J., Xia, S., Warshel, A., & Wu, H. (2022). Electrostatic influence on IL-1 transport through the GSDMD pore. Proceedings of the National Academy of Sciences, 119(6), e2120287119.

Liu, Y., Xue, N., Zhang, B., Lv, H., & Li, S. (2022). Cold Stress Induced Liver Injury of Mice through Activated NLRP3/Caspase-1/GSDMD Pyroptosis Signaling Pathway. Biomolecules, 12(7), 927.

Jiang, S., Zhang, H., Li, X., Yi, B., Huang, L., Hu, Z., ... & Zhang, W. (2021). Vitamin D/VDR attenuate cisplatin-induced AKI by down-regulating NLRP3/Caspase-1/GSDMD pyroptosis pathway. The Journal of Steroid Biochemistry and Molecular Biology, 206, 105789.

Zhang, J., Dai, Y., Yang, Y., & Xu, J. (2021). Calcitriol alleviates hyperosmotic stress-induced corneal epithelial cell damage via inhibiting the NLRP3–ASC–caspase-1–GSDMD pyroptosis pathway in dry eye disease. Journal of Inflammation Research, 14, 2955.

Yan, H., Luo, B., Wu, X., Guan, F., Yu, X., Zhao, L., ... & Yuan, J. (2021). Cisplatin induces pyroptosis via activation of MEG3/NLRP3/caspase-1/GSDMD pathway in triple-negative breast cancer. International Journal of Biological Sciences, 17(10), 2606.

Li, W., Deng, M., Loughran, P. A., Yang, M., Lin, M., Yang, C., ... & Scott, M. J. (2020). LPS induces active HMGB1 release from hepatocytes into exosomes through the coordinated activities of TLR4 and caspase-11/GSDMD signaling. Frontiers in Immunology, 11, 229.

Yang, Y., Liu, P. Y., Bao, W., Chen, S. J., Wu, F. S., & Zhu, P. Y. (2020). Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. BMC cancer, 20, 1-19.

Schwarzer, R., Jiao, H., Wachsmuth, L., Tresch, A., & Pasparakis, M. (2020). FADD and caspase-8 regulate gut homeostasis and inflammation by controlling MLKL-and GSDMD-mediated death of intestinal epithelial cells. Immunity, 52(6), 978-993.

Karmakar, M., Minns, M., Greenberg, E. N., Diaz-Aponte, J., Pestonjamasp, K., Johnson, J. L., ... & Pearlman, E. (2020). N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis. Nature communications, 11(1), 2212.

Pandeya, A., Li, L., Li, Z., & Wei, Y. (2019). Gasdermin D (GSDMD) as a new target for the treatment of infection. Medchemcomm, 10(5), 660-667.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

GSDMD Matched Antibody Pair (505)

Antibody Pairs

GSDMD Matched Antibody Pair (505)

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GSDMD Matched Antibody Pair (505)

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Isotype control