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GSN Matched Antibody Pair (506) (APMAB-506LY)

This antibody pair set can be used for detecting and quantifying protein level of human GSN.
See all GSN antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-GSN polyclonal antibody, 100 ug
Detection Antibody
Anti-GSN Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alternative Names
Gelsolin; Actin-Depolymerizing Factor; Brevin; AGEL; ADF; Gelsolin (Amyloidosis, Finnish Type); Amyloidosis, Finnish Type;
Entrez Gene ID
2934
UniProt ID
P06396

Zhang, Q., Tang, S. L., Zhao, Z. W., & Tang, C. K. (2023). Role and therapeutic potential of gelsolin in atherosclerosis. Journal of Molecular and Cellular Cardiology.

Onuma, T., Asare-Werehene, M., Yoshida, Y., & Tsang, B. K. (2022). Exosomal Plasma Gelsolin Is an Immunosuppressive Mediator in the Ovarian Tumor Microenvironment and a Determinant of Chemoresistance. Cells, 11(20), 3305.

Wu, Y., Zheng, J., Yan, Y., Liu, J., & Zhou, Y. (2022). Gelsolin can be a prognostic biomarker and correlated with immune infiltrates in gastric cancer. International Journal of General Medicine, 927-936.

Feldt, J., Schicht, M., Welss, J., Gelse, K., Sesselmann, S., Tsokos, M., ... & Paulsen, F. (2022). Production and secretion of gelsolin by both human macrophage-and fibroblast-like synoviocytes and GSN modulation in the synovial fluid of patients with various forms of arthritis. Biomedicines, 10(3), 723.

Potrč, M., Volk, M., de Rosa, M., Pižem, J., Teran, N., Jaklič, H., ... & Fakin, A. (2021). Clinical and histopathological features of gelsolin amyloidosis associated with a novel GSN variant p. Glu580Lys. International journal of molecular sciences, 22(3), 1084.

Jana, S., Aujla, P., Hu, M., Kilic, T., Zhabyeyev, P., McCulloch, C. A., ... & Kassiri, Z. (2021). Gelsolin is an important mediator of Angiotensin II‐induced activation of cardiac fibroblasts and fibrosis. The FASEB Journal, 35(10), e21932.

Zhang, Y., Luo, X., Lin, J., Fu, S., Feng, P., Su, H., ... & Deng, W. (2020). Gelsolin promotes cancer progression by regulating epithelial-mesenchymal transition in hepatocellular carcinoma and correlates with a poor prognosis. Journal of Oncology, 2020.

Chen, Z., Li, K., Yin, X., Li, H., Li, Y., Zhang, Q., ... & Qiu, Y. (2019). Lower expression of gelsolin in colon cancer and its diagnostic value in colon cancer patients. Journal of Cancer, 10(5), 1288.

Wittmann, J., Dieckow, J., Schröder, H., Hampel, U., Garreis, F., Jacobi, C., ... & Schicht, M. (2018). Plasma gelsolin promotes re-epithelialization. Scientific Reports, 8(1), 13140.

Feldt, J., Schicht, M., Garreis, F., Welss, J., Schneider, U. W., & Paulsen, F. (2018). Structure, regulation and related diseases of the actin-binding protein gelsolin. Expert reviews in molecular medicine, 20, e7.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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