GSN Matched Antibody Pair (506) (APMAB-506LY)

Name: GSN Matched Antibody Pair (506)
SKU: APMAB-506LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-GSN polyclonal antibody, 100 ug

Detection Antibody

Anti-GSN Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative Names

Gelsolin; Actin-Depolymerizing Factor; Brevin; AGEL; ADF; Gelsolin (Amyloidosis, Finnish Type); Amyloidosis, Finnish Type;

Entrez Gene ID

2934

UniProt ID

P06396

More Infomation

Zhang, Q., Tang, S. L., Zhao, Z. W., & Tang, C. K. (2023). Role and therapeutic potential of gelsolin in atherosclerosis. Journal of Molecular and Cellular Cardiology.

Onuma, T., Asare-Werehene, M., Yoshida, Y., & Tsang, B. K. (2022). Exosomal Plasma Gelsolin Is an Immunosuppressive Mediator in the Ovarian Tumor Microenvironment and a Determinant of Chemoresistance. Cells, 11(20), 3305.

Wu, Y., Zheng, J., Yan, Y., Liu, J., & Zhou, Y. (2022). Gelsolin can be a prognostic biomarker and correlated with immune infiltrates in gastric cancer. International Journal of General Medicine, 927-936.

Feldt, J., Schicht, M., Welss, J., Gelse, K., Sesselmann, S., Tsokos, M., ... & Paulsen, F. (2022). Production and secretion of gelsolin by both human macrophage-and fibroblast-like synoviocytes and GSN modulation in the synovial fluid of patients with various forms of arthritis. Biomedicines, 10(3), 723.

Potrč, M., Volk, M., de Rosa, M., Pižem, J., Teran, N., Jaklič, H., ... & Fakin, A. (2021). Clinical and histopathological features of gelsolin amyloidosis associated with a novel GSN variant p. Glu580Lys. International journal of molecular sciences, 22(3), 1084.

Jana, S., Aujla, P., Hu, M., Kilic, T., Zhabyeyev, P., McCulloch, C. A., ... & Kassiri, Z. (2021). Gelsolin is an important mediator of Angiotensin II‐induced activation of cardiac fibroblasts and fibrosis. The FASEB Journal, 35(10), e21932.

Zhang, Y., Luo, X., Lin, J., Fu, S., Feng, P., Su, H., ... & Deng, W. (2020). Gelsolin promotes cancer progression by regulating epithelial-mesenchymal transition in hepatocellular carcinoma and correlates with a poor prognosis. Journal of Oncology, 2020.

Chen, Z., Li, K., Yin, X., Li, H., Li, Y., Zhang, Q., ... & Qiu, Y. (2019). Lower expression of gelsolin in colon cancer and its diagnostic value in colon cancer patients. Journal of Cancer, 10(5), 1288.

Wittmann, J., Dieckow, J., Schröder, H., Hampel, U., Garreis, F., Jacobi, C., ... & Schicht, M. (2018). Plasma gelsolin promotes re-epithelialization. Scientific Reports, 8(1), 13140.

Feldt, J., Schicht, M., Garreis, F., Welss, J., Schneider, U. W., & Paulsen, F. (2018). Structure, regulation and related diseases of the actin-binding protein gelsolin. Expert reviews in molecular medicine, 20, e7.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Gsn ELISA Kit (CAT#: V2LY-0626-LY1099)

Human GSN ELISA Kit (CAT#: V2LY-0626-LY1509)

Cattle GSN ELISA Kit (CAT#: V2LY-0626-LY2292)

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Mouse Anti-GSN Recombinant Antibody (CBLG1-2993) (CAT#: CBMAB-G0866-LY)

Mouse Gsn ELISA Kit (CAT#: V2LY-0626-LY1099)

Mouse Anti-GSN Recombinant Antibody (35B2) (CAT#: CBMAB-G5273-LY)

Alpaca Anti-GSN Recombinant VHH Antibody (6A2) (CAT#: CBMAB-1302CQ)

Mouse Anti-GSN Recombinant Antibody (CBT2926) (CAT#: V2LY-0625-LY1507)

Rabbit Anti-GSN Recombinant Antibody (
16H9) (CAT#: V2LY-0725-LY1572)

Mouse Anti-GSN Recombinant Antibody (3G5) (CAT#: CBMAB-G0868-LY)

Mouse Anti-GSN Recombinant Antibody (CBLG1-256) (CAT#: CBMAB-G0871-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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