HSPA13 Matched Antibody Pair (575) (APMAB-575LY)

Name: HSPA13 Matched Antibody Pair (575)
SKU: APMAB-575LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-HSPA13 polyclonal antibody, 100 ug

Detection Antibody

Anti-HSPA13 Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. The encoded protein contains an ATPase domain and has been shown to associate with a ubiquitin-like protein. [provided by RefSeq, Jul 2008]

Alternative Names

Heat Shock Protein Family A (Hsp70) Member 13; Stress-70 Protein Chaperone Microsome-Associated 60 KDa Protein; Stress 70 Protein Chaperone, Microsome-Associated, 60kDa; Stress 70 Protein Chaperone, Microsome-Associated, 60kD; Heat Shock Protein 70kDa Family, Member 13; STCH;

Entrez Gene ID

6782

UniProt ID

P48723

More Infomation

References

Espinoza, M. F., Nguyen, K. K., Sycks, M. M., Lyu, Z., Quanrud, G. M., Montoya, M. R., & Genereux, J. C. (2022). Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation. Journal of Biological Chemistry, 298(12).

Zhai, B., Liu, X., Xu, Y., Zhu, G., Zhou, S., He, Y., ... & Wang, R. (2022). Single-cell atlas of splenocytes reveals a critical role of a novel plasma cell‒specific marker Hspa13 in antibody class-switching recombination and somatic hypermutation. Molecular Immunology, 141, 79-86.

Espinoza, M. F., Nguyen, K. K., Sycks, M. M., Lyu, Z., Montoya, M. R., & Genereux, J. C. (2022). Hspa13 Regulates Endoplasmic Reticulum and Cytosolic Proteostasis Through Modulation of Protein Translocation. bioRxiv, 2022-06.

Gao, C., Deng, J., Zhang, H., Li, X., Gu, S., Zheng, M., ... & Feng, X. H. (2021). HSPA13 facilitates NF-κB–mediated transcription and attenuates cell death responses in TNFα signaling. Science Advances, 7(41), eabh1756.

He, Y., Xu, R., Zhai, B., Fang, Y., Hou, C., Xing, C., ... & Wang, R. (2020). Hspa13 promotes plasma cell production and antibody secretion. Frontiers in Immunology, 11, 913.

Yun, C. H., Kim, Y. C., & Jeong, B. H. (2018). The First Report on Single Nucleotide Polymorphisms of the HSPA13 Gene in Koreans. Russian Journal of Genetics, 54, 353-357.

Genereux, J. (2018). The ER Hsp70 Hspa13 Redirects an Amyloidogenic Protein to Aggregation. The FASEB Journal, 32, 794-10.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-HSPA13 (AA 375-470) Recombinant Antibody (CBFYH-2170)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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SDS
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Second antibody and isotype control

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