Human CABP1 ELISA Kit (V2LY-0626-LY3717)

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Tested Data
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.033 ng/mL
Detection Range
0.07-15 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
39.8 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
calcium binding protein 1
Function
Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs)(PubMed:14570872).
Inhibits agonist-induced intracellular calcium signaling (PubMed:15980432).
Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels (PubMed:11865310).
Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function (PubMed:15140941).
Suppresses the calcium-dependent inactivation of CACNA1D (By similarity).
Inhibits TRPC5 channels (PubMed:15895247).
Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina (By similarity).
Biological Process
Negative regulation of protein import into nucleus Source: UniProtKB
Response to stimulus Source: UniProtKB-KW
Visual perception Source: UniProtKB
Cellular Location
Golgi apparatus; Cytoskeleton; Cell membrane; Perinuclear region; Postsynaptic density. L-CaBP1 is associated most likely with the cytoskeletal structures, whereas S-CaBP1 is localized at or near the plasma membrane.
Isoform L-CaBP1: Cytoskeleton. L-CaBP1 is associated most likely with the cytoskeletal structures.
Isoform S-CaBP1: Cell membrane; Cell cortex. S-CaBP1 is localized at or near the plasma membrane.
PTM
Phosphorylated. The phosphorylation regulates the activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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