Human CALB1 ELISA Kit (V2LY-0626-LY3486)

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Tested Data
Datasheet
SDS
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Basic Information

Sensitivity
0.0015 ng/mL
Detection Range
0.003-0.9 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
30.0 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Calbindin 1
Function
Buffers cytosolic calcium. May stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
Biological Process
Amyloid fibril formation Source: Reactome
Cellular response to organic substance Source: Ensembl
Cochlea development Source: Ensembl
Locomotory behavior Source: Ensembl
Long-term memory Source: UniProtKB
Metanephric collecting duct development Source: Ensembl
Metanephric connecting tubule development Source: Ensembl
Metanephric distal convoluted tubule development Source: Ensembl
Metanephric part of ureteric bud development Source: Ensembl
Regulation of cytosolic calcium ion concentration Source: GO_Central
Regulation of long-term synaptic potentiation Source: GO_Central
Regulation of presynaptic cytosolic calcium ion concentration Source: GO_Central
Retina layer formation Source: Ensembl
Short-term memory Source: UniProtKB
Cellular Location
Cuticular plate; Cytosol; Postsynaptic cytosol; Presynaptic cytosol; Extracellular exosome; Nucleus; Axon; Calyx of Held; Dendrite; Dendritic spine; GABA-ergic synapse; Glutamatergic synapse; Hippocampal mossy fiber to CA3 synapse; Neuron projection; Neuronal cell body; Stereocilium; Synapse; Terminal bouton

Castrogiovanni, P., Sanfilippo, C., Imbesi, R., Maugeri, G., Lo Furno, D., Tibullo, D., ... & Di Rosa, M. (2021). Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients. Cells, 10(4), 882.

of Wang, N., Lavasseur, C. M., Yan, H., Younger, S., Glader, B., Sakamoto, K. M., ... & Narla, A. (2020). Targeting of Calbindin 1 (CALB1) Rescues Erythropoiesis in a Human Model of Diamond Blackfan Anemia: Implications for Novel Therapies. Blood, 136, 4.

Jin, C., Lin, T., & Shan, L. (2019). Downregulation of calbindin 1 by miR-454-3p suppresses cell proliferation in nonsmall cell lung cancer in vitro. Cancer biotherapy & radiopharmaceuticals, 34(2), 119-127.

Cao, L. Q., Wang, Y. N., Liang, M., & Pan, M. Z. (2019). CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells. Molecular medicine reports, 19(6), 5097-5104.

Goffigan-Holmes, J., Sanabria, D., Diaz, J., Flock, D., & Chavez-Valdez, R. (2018). Calbindin-1 expression in the hippocampus following neonatal hypoxia-ischemia and therapeutic hypothermia and deficits in spatial memory. Developmental neuroscience, 40(5-6), 508-522.

Huang, Z., Fan, G., & Wang, D. (2017). Downregulation of calbindin 1, a calcium-binding protein, reduces the proliferation of osteosarcoma cells. Oncology letters, 13(5), 3727-3733.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rat Calb1 ELISA Kit (CAT#: V2LY-0626-LY3095)

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Rat Calb1 ELISA Kit (CAT#: V2LY-0626-LY3095)

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Isotype control

For research use only. Not intended for any clinical use.

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