Mouse Adamdec1 ELISA Kit (V2LY-0626-LY1992)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0093 ng/mL
Detection Range
0.02-4.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
53.0 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
ADAM-like, decysin 1
Function
May play an important role in the control of the immune response and during pregnancy.
Biological Process
Immune response
Negative regulation of cell adhesion
Cellular Location
Secreted

Liu, T., Deng, Z., Xie, H., Chen, M., Xu, S., Peng, Q., ... & Li, J. (2020). ADAMDEC1 promotes skin inflammation in rosacea via modulating the polarization of M1 macrophages. Biochemical and biophysical research communications, 521(1), 64-71.

Kumagai, T., Fan, S., & Smith, A. M. (2020). ADAMDEC1 and its role in inflammatory disease and cancer. Metalloproteinases In Medicine, 7, 15-28.

Jimenez-Pascual, A., Lathia, J. D., & Siebzehnrubl, F. A. (2020). ADAMDEC1 and FGF2/FGFR1 signaling constitute a positive feedback loop to maintain GBM cancer stem cells. Molecular & cellular oncology, 7(1), 1684787.

Hale, J. S., Jimenez-Pascual, A., Kordowski, A., Pugh, J., Rao, S., Silver, D. J., ... & Siebzehnrubl, F. A. (2019). ADAMDEC1 maintains a novel growth factor signaling loop in cancer stem cells. bioRxiv, 531509.

Shi, L., Li, S., Maurer, K., Zhang, Z., Petri, M., & Sullivan, K. E. (2018). Enhancer RNA and NFκB-dependent P300 regulation of ADAMDEC1. Molecular immunology, 103, 312-321.

Sugimoto, N., Nakayama, T., Kasai, Y., Asaka, D., Mitsuyoshi, R., Tsurumoto, T., ... & Haruna, S. I. (2018). The role of ADAM-like decysin 1 in non-eosinophilic chronic rhinosinusitis with nasal polyps. Acta oto-laryngologica, 138(9), 830-836.

Yako, Y., Hayashi, T., Takeuchi, Y., Ishibashi, K., Kasai, N., Sato, N., ... & Fujita, Y. (2018). ADAM-like Decysin-1 (ADAMDEC1) is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cells. Scientific reports, 8(1), 1-11.

Lund, J., Elimar Bitsch, A. M., Grønbech Rasch, M., Enoksson, M., Troeberg, L., Nagase, H., ... & Petersen, H. H. (2018, January). Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma. In MAbs (Vol. 10, No. 1, pp. 118-128). Taylor & Francis.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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