Human FABP7 ELISA Kit (V2LY-0626-LY4574)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.29 ng/mL
Detection Range
0.5-200 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
14.9 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Fatty Acid Binding Protein 7
Research Area
B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity).
Biological Process
Epithelial cell proliferation Source: Ensembl
Negative regulation of cell population proliferation Source: ProtInc
Nervous system development Source: ProtInc
Cellular Location
Cytoplasm

Zeng, F., Luo, L., Song, M., & Li, D. (2022). Silencing of circular RNA PUM1 inhibits clear cell renal cell carcinoma progression through the miR-340-5p/FABP7 axis. Journal of Receptors and Signal Transduction, 42(2), 141-150.

Nowowiejska, J., Baran, A., Hermanowicz, J. M., Sieklucka, B., Krahel, J. A., Kiluk, P., ... & Flisiak, I. (2022). Fatty Acid-Binding Protein 7 (FABP-7), Glutamic Acid and Neurofilament Light Chain (NFL) as Potential Markers of Neurodegenerative Disorders in Psoriatic Patients—A Pilot Study. Journal of clinical medicine, 11(9), 2430.

Umaru, B. A., Kagawa, Y., Shil, S. K., Arakawa, N., Pan, Y., Miyazaki, H., ... & Owada, Y. (2021). Ligand bound fatty acid binding protein 7 (FABP7) drives melanoma cell proliferation via modulation of wnt/β-catenin signaling. Pharmaceutical research, 38(3), 479-490.

Choi, W. S., Xu, X., Goruk, S., Wang, Y., Patel, S., Chow, M., ... & Godbout, R. (2021). FABP7 Facilitates Uptake of Docosahexaenoic Acid in Glioblastoma Neural Stem-like Cells. Nutrients, 13(8), 2664.

Chen, J., Liu, X., Zhang, S., Chen, J., Sun, H., Zhang, L., & Zhang, Q. (2020). Molecular mechanism with regard to the binding selectivity of inhibitors toward FABP5 and FABP7 explored by multiple short molecular dynamics simulations and free energy analyses. Physical Chemistry Chemical Physics, 22(4), 2262-2275.

Killoy, K. M., Harlan, B. A., Pehar, M., & Vargas, M. R. (2020). FABP7 upregulation induces a neurotoxic phenotype in astrocytes. Glia, 68(12), 2693-2704.

Kagawa, Y., Umaru, B. A., Ariful, I., Shil, S. K., Miyazaki, H., Yamamoto, Y., ... & Owada, Y. (2019). Role of FABP7 in tumor cell signaling. Advances in biological regulation, 71, 206-218.

Cordero, A., Kanojia, D., Miska, J., Panek, W. K., Xiao, A., Han, Y., ... & Lesniak, M. S. (2019). FABP7 is a key metabolic regulator in HER2+ breast cancer brain metastasis. Oncogene, 38(37), 6445-6460.

Islam, A., Kagawa, Y., Miyazaki, H., Shil, S. K., Umaru, B. A., Yasumoto, Y., ... & Owada, Y. (2019). FABP7 protects astrocytes against ROS toxicity via lipid droplet formation. Molecular Neurobiology, 56(8), 5763-5779.

Yasumoto, Y., Miyazaki, H., Ogata, M., Kagawa, Y., Yamamoto, Y., Islam, A., ... & Owada, Y. (2018). Glial fatty acid-binding protein 7 (FABP7) regulates neuronal leptin sensitivity in the hypothalamic arcuate nucleus. Molecular Neurobiology, 55(12), 9016-9028.

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For research use only. Not intended for any clinical use.

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