Human FGL2 ELISA Kit (V2LY-0626-LY4588)

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Tested Data
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Basic Information

Sensitivity
0.058 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
50.2 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Fibrinogen Like 2
Function
May play a role in physiologic lymphocyte functions at mucosal sites.
Biological Process
Negative regulation of defense response to virus Source: Ensembl
Negative regulation of dendritic cell antigen processing and presentation Source: Ensembl
Negative regulation of macrophage antigen processing and presentation Source: Ensembl
Negative regulation of memory T cell differentiation Source: Ensembl
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell Source: Ensembl
Cellular Location
Secreted

Shao, W., Huang, Y., Wang, L., Li, P., Jia, Y., & Zhang, J. (2023). Expression of fibrinogen-like protein 2 (Fgl2) on Toll-like receptor 9 (TLR9) expression in autoimmune myelitis. International Immunopharmacology, 114, 109539.

Zhang, S., Rao, G., Heimberger, A., & Li, S. (2022). Fibrinogen-like protein 2: its biological function across cell types and the potential to serve as an immunotherapy target for brain tumors. Cytokine & Growth Factor Reviews.

Pulkka, O. P., Viisanen, L., Tynninen, O., Laaksonen, M., Reichardt, P., Reichardt, A., ... & Joensuu, H. (2022). Fibrinogen‐like protein 2 in gastrointestinal stromal tumour. Journal of cellular and molecular medicine, 26(4), 1083-1094.

Liu, B. Q., Bao, Z. Y., Zhu, J. Y., & Liu, H. (2021). Fibrinogen‑like protein 2 promotes the accumulation of myeloid‑derived suppressor cells in the hepatocellular carcinoma tumor microenvironment. Oncology letters, 21(1), 1-1.

Robineau-Charette, P., Grynspan, D., Benton, S. J., Gaudet, J., Cox, B. J., Vanderhyden, B. C., & Bainbridge, S. A. (2020). Fibrinogen-like protein 2-associated transcriptional and histopathological features of immunological preeclampsia. Hypertension, 76(3), 910-921.

Hu, J., Wang, H., Li, X., Liu, Y., Mi, Y., Kong, H., ... & Wang, X. (2020). Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder. Theranostics, 10(21), 9702.

Wu, S., Li, M., Xu, F., Li, G. Q., Han, B. O., He, X. D., ... & Xu, G. L. (2020). Fibrinogen-like protein 2 deficiency aggravates renal fibrosis by facilitating macrophage polarization. Biomedicine & Pharmacotherapy, 130, 110468.

Latha, K., Yan, J., Yang, Y., Gressot, L. V., Kong, L. Y., Manyam, G., ... & Rao, G. (2019). The role of fibrinogen-like protein 2 on immunosuppression and malignant progression in glioma. JNCI: Journal of the National Cancer Institute, 111(3), 292-300.

Chen, T. J., Ji, M. X., Tao, Z. Q., Fu, Q. Y., Xiong, K., & Cheng, B. (2019). The relationship between serum fibrinogen-like protein 2 concentrations and 30-day mortality of patients with traumatic brain injury. Clinica Chimica Acta, 489, 53-57.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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