Human GLUL ELISA Kit (V2LY-0626-LY4184)
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Basic Information
- Pre-coated ELISA Plate: 12 wells * 8 detachable strips
- Standard solution: 0.5ml x1
- Standard diluent: 3ml x1
- Streptavidin-HRP: 6ml x1
- Stop solution: 6ml x1
- Substrate solution A: 6ml x1
- Substrate solution B: 6ml x1
- Wash buffer concentrate (25x): 20ml x1
- Biotinylated antibody: 1ml x1
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity).
Essential for proliferation of fetal skin fibroblasts (PubMed:18662667).
Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation (PubMed:30158707).
May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ (PubMed:30158707).
Plays a role in ribosomal 40S subunit biogenesis (PubMed:26711351).
Angiogenesis Source: UniProtKB-KW
Cell population proliferation Source: UniProtKB
Cellular response to starvation Source: Ensembl
Glutamate catabolic process Source: BHF-UCL
Glutamine biosynthetic process Source: GO_Central
Positive regulation of epithelial cell proliferation Source: Ensembl
Positive regulation of insulin secretion Source: Ensembl
Positive regulation of synaptic transmission, glutamatergic Source: Ensembl
Protein palmitoylation Source: UniProtKB
Regulation of endothelial cell migration Source: UniProtKB
Regulation of protein localization to nucleolus Source: UniProtKB
Regulation of sprouting angiogenesis Source: UniProtKB
Response to glucose Source: Ensembl
Ribosome biogenesis Source: UniProtKB
Rare developmental disorder with severe brain malformation resulting in multi-organ failure and neonatal death. Glutamine is largely absent from affected patients serum, urine and cerebrospinal fluid.
Ubiquitinated by ZNRF1.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
GLUL Matched Antibody Pair (489) (CAT#: APMAB-489LY)
Antibody Pairs
GLUL Matched Antibody Pair (489) (CAT#: APMAB-489LY)
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Mouse Anti-GLUL Recombinant Antibody (CBLG1-3189) (CAT#: CBMAB-G3937-LY)
GLUL Matched Antibody Pair (489) (CAT#: APMAB-489LY)
Mouse Anti-GLUL Recombinant Antibody (CBFYH-3449) (CAT#: CBMAB-H3996-FY)
Mouse Anti-GLUL Recombinant Antibody (CBLG1-1323) (CAT#: CBMAB-G3943-LY)
Mouse Anti-GLUL Recombinant Antibody (BA0405) (CAT#: CBMAB-0350CQ)
Mouse Anti-GLUL Recombinant Antibody (CBLG1-1329) (CAT#: CBMAB-G3949-LY)
Rabbit Anti-GLUL Recombinant Antibody (BA0124) (CAT#: CBMAB-0349CQ)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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