Human HOXA10 ELISA Kit (V2LY-0626-LY4691)

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Tested Data
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0072 ng/mL
Detection Range
0.015-3 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
42.4 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
HOMEOBOX A10
Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'.
Biological Process
Anterior/posterior pattern specification Source: Ensembl
Embryonic limb morphogenesis Source: Ensembl
Male gonad development Source: Ensembl
Multicellular organism development Source: ProtInc
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Prostate gland development Source: Ensembl
Proximal/distal pattern formation Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Response to estrogen Source: Ensembl
Response to testosterone Source: Ensembl
Single fertilization Source: Ensembl
Skeletal system development Source: Ensembl
Spermatogenesis Source: ProtInc
Uterus development Source: Ensembl
Cellular Location
Nucleus

Ekanayake, D. L., Małopolska, M. M., Schwarz, T., Tuz, R., & Bartlewski, P. M. (2022). The roles and expression of HOXA/Hoxa10 gene: A prospective marker of mammalian female fertility?. Reproductive Biology, 22(2), 100647.

Nie, S., Zhang, L., Liu, J., Wan, Y., Jiang, Y., Yang, J., ... & Cheng, W. (2021). ALKBH5-HOXA10 loop-mediated JAK2 m6A demethylation and cisplatin resistance in epithelial ovarian cancer. Journal of Experimental & Clinical Cancer Research, 40, 1-18.

Li, H., You, J., Xue, H., Tan, X., & Chao, C. (2020). CircCTDP1 promotes nasopharyngeal carcinoma progression via a microRNA‑320b/HOXA10/TGFβ2 pathway. International journal of molecular medicine, 45(3), 836-846.

Guo, C., Ju, Q. Q., Zhang, C. X., Gong, M., Li, Z. L., & Gao, Y. Y. (2020). Overexpression of HOXA10 is associated with unfavorable prognosis of acute myeloid leukemia. BMC cancer, 20, 1-12.

Yan, X., Cong, B., Chen, Q., Liu, L., Luan, X., Du, J., & Cao, M. (2020). Silencing lncRNA HOXA10-AS decreases cell proliferation of oral cancer and HOXA10-antisense RNA can serve as a novel prognostic predictor. Journal of International Medical Research, 48(8), 0300060520934254.

Hatanaka, Y., de Velasco, M. A., Oki, T., Shimizu, N., Nozawa, M., Yoshimura, K., ... & Uemura, H. (2019). HOXA10 expression profiling in prostate cancer. The Prostate, 79(5), 554-563.

Song, C., Han, Y., Luo, H., Qin, Z., Chen, Z., Liu, Y., ... & Zhou, C. (2019). HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer. Cancer Medicine, 8(12), 5651-5661.

Chen, W., Wu, G., Zhu, Y., Zhang, W., Zhang, H., Zhou, Y., & Sun, P. (2019). HOXA10 deteriorates gastric cancer through activating JAK1/STAT3 signaling pathway. Cancer management and research, 6625-6635.

Shao, M., Yang, Q., Zhu, W., Jin, H., Wang, J., Song, J., ... & Lv, X. (2018). LncHOXA10 drives liver TICs self-renewal and tumorigenesis via HOXA10 transcription activation. Molecular Cancer, 17(1), 1-12.

Guo, L. M., Ding, G. F., Xu, W., Ge, H., Jiang, Y., Chen, X. J., & Lu, Y. (2018). MiR-135a-5p represses proliferation of HNSCC by targeting HOXA10. Cancer Biology & Therapy, 19(11), 973-983.

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For research use only. Not intended for any clinical use.

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