Human KCNJ15 ELISA Kit (V2LY-0626-LY1982)

Name: Human KCNJ15 ELISA Kit
SKU: V2LY-0626-LY1982
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.011 ng/mL

Detection Range

0.02-4.5 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Human

Assay Type

Sandwich

Reactivity

Human

Assay Time

1.5 h

Molecule Mass

42.6 kDa

Components

Pre-coated ELISA plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

potassium inwardly-rectifying channel, subfamily J, member 15

Function

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Biological Process

Potassium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Potassium ion transportManual Assertion Based On ExperimentTAS:ProtInc
Regulation of ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Membrane

Topology

Cytoplasmic: 1-63
Helical: 64-88
Extracellular: 89-113
Helical: 114-125
Pore-forming: 126-132
Extracellular: 133-141
Helical: 142-163
Cytoplasmic: 164-375

Zhou, S. Z., Shen, L., Fu, Z. B., Li, H., Pan, Y. L., & Yu, R. Z. (2023). Exploring the common diagnostic gene KCNJ15 and shared pathway of ankylosing spondylitis and ulcerative colitis through integrated bioinformatics. Frontiers in Physiology, 14, 624.

Qiao, X., Zhang, Y., Zhang, Z., Niu, N., Li, H., Sun, L., ... & Liu, C. (2023). KCNJ15 deficiency promotes drug resistance via affecting the function of lysosomes. Asian Journal of Pharmaceutical Sciences, 18(3), 100814.

Wang, S., Li, Z., Ding, X., Zhao, Z., Zhang, M., Xu, H., ... & Dai, L. (2022). Integrative Analyses Identify KCNJ15 as a Candidate Gene in Patients with Epilepsy. Neurology and Therapy, 11(4), 1767-1776.

Nakamura, S., Kanda, M., Koike, M., Shimizu, D., Umeda, S., Hattori, N., ... & Kodera, Y. (2020). KCNJ15 expression and malignant behavior of esophageal squamous cell carcinoma. Annals of Surgical Oncology, 27, 2559-2568.

Nakamura, S., Kanda, M., & Kodera, Y. (2020). ASO Author Reflections: KCNJ15 Expression and Malignant Behavior of Esophageal Squamous Cell Carcinoma. Annals of Surgical Oncology, 27, 2569-2570.

Liu, Y., Wang, H., Ni, B., Zhang, J., Li, S., Huang, Y., ... & Li, Z. (2019). Loss of KCNJ15 expression promotes malignant phenotypes and correlates with poor prognosis in renal carcinoma. Cancer Management and Research, 1211-1220.

Liu, Y., Ni, B., Li, S., Huang, Y., Mei, H., & Li, Z. (2018). AB026. Loss of KCNJ15 expression promotes malignant phenotypes and correlates with poor prognosis in renal carcinoma. Translational Andrology and Urology, 7(Suppl 5).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-KCNJ15 Recombinant Antibody (1F8) (CAT#: CBMAB-K0566-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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