Human OLIG1 ELISA Kit (V2LY-0626-LY1093)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.025 ng/mL
Detection Range
0.5-150 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
27.9 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
oligodendrocyte transcription factor 1
Function
Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity).
Biological Process
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Neuron fate commitmentIEA:Ensembl
Oligodendrocyte developmentIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus

Verma, R., Chen, X., Xin, D., Luo, Z., Ogurek, S., Xin, M., ... & Lu, Q. R. (2023). Olig1/2-Expressing Intermediate Lineage Progenitors Are Predisposed to PTEN/p53-Loss–Induced Gliomagenesis and Harbor Specific Therapeutic Vulnerabilities. Cancer Research, 83(6), 890-905.

Zhao, H., Gao, X. Y., Wu, X. J., Zhang, Y. B., & Wang, X. F. (2022). The Shh/Gli1 signaling pathway regulates regeneration via transcription factor Olig1 expression after focal cerebral ischemia in rats. Neurological Research, 44(4), 318-330.

Mashayekhi, F., Shabani, S., Talesh Sasani, S., & Salehi, Z. (2021). The enhancing effect of electromagnetic field on the expression of Oligodendrocyte transcription factor 1 and 2 (Olig1/2) in the mice cerebral cortex. Nova Biologica Reperta, 7(4), 374-380.

Joshi, M., Shah, D. P., & Krishnakumar, A. (2021). Extreme glycemic fluctuations debilitate NRG1, ErbB receptors and Olig1 function: association with regeneration, cognition and mood alterations during diabetes. Molecular Neurobiology, 58(9), 4727-4744.

Wang, X., Su, Y., Li, T., Yu, G., Wang, Y., Chen, X., ... & Niu, J. (2021). Quetiapine promotes oligodendroglial process outgrowth and membrane expansion by orchestrating the effects of Olig1. Glia, 69(7), 1709-1722.

Panagopoulos, I., Gorunova, L., Johannsdottir, I. M. R., Andersen, K., Holth, A., Beiske, K., & Heim, S. (2020). Chromosome Translocation t (14; 21)(q11; q22) Activates Both OLIG1 and OLIG2 in Pediatric T-cell Lymphoblastic Malignancies and May Signify Adverse Prognosis. Cancer Genomics & Proteomics, 17(1), 41-48.

Zhao, H., Gao, X. Y., Liu, Z. H., Lin, J. W., Wang, S. P., Wang, D. X., & Zhang, Y. B. (2019). Effects of the transcription factor Olig1 on the differentiation and remyelination of oligodendrocyte precursor cells after focal cerebral ischemia in rats. Molecular Medicine Reports, 20(5), 4603-4611.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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