Human OSBPL2 ELISA Kit (V2LY-0626-LY3784)

Lin, K., Zhao, Y., Tang, Y., Chen, Y., Lin, M., & He, L. (2024). Collagen I-induced VCAN/ERK signaling and PARP1/ZEB1-mediated metastasis facilitate OSBPL2 defect to promote colorectal cancer progression. Cell Death & Disease, 15(1), 85.

Koh, Y. I., Oh, K. S., Kim, J. A., Noh, B., Choi, H. J., Joo, S. Y., ... & Gee, H. Y. (2022). OSBPL2 mutations impair autophagy and lead to hearing loss, potentially remedied by rapamycin. Autophagy, 18(11), 2593-2614.

Shi, H., Wang, H., Zhang, C., Lu, Y., Yao, J., Chen, Z., ... & Cao, X. (2022). Mutations in OSBPL2 cause hearing loss associated with primary cilia defects via sonic hedgehog signaling. JCI insight, 7(4).

Wang, T., Wei, Q., Liang, L., Tang, X., Yao, J., Lu, Y., ... & Cao, X. (2020). OSBPL2 Is Required for the Binding of COPB1 to ATGL and the Regulation of Lipid Droplet Lipolysis. IScience, 23(7).

Shi, H., Wang, H., Yao, J., Lin, C., Wei, Q., Lu, Y., & Cao, X. (2020). Comparative transcriptome analysis of auditory OC-1 cells and zebrafish inner ear tissues in the absence of human OSBPL2 orthologues. Biochemical and Biophysical Research Communications, 521(1), 42-49.

Zhang, C., Zhang, H., Zhang, M., Lin, C., Wang, H., Yao, J., ... & Cao, X. (2019). OSBPL2 deficiency upregulate SQLE expression increasing intracellular cholesterol and cholesteryl ester by AMPK/SP1 and SREBF2 signalling pathway. Experimental cell research, 383(2), 111512.

Yao, J., Zeng, H., Zhang, M., Wei, Q., Wang, Y., Yang, H., ... & Dai, Y. (2019). OSBPL2-disrupted pigs recapitulate dual features of human hearing loss and hypercholesterolaemia. Journal of genetics and genomics, 46(8), 379-387.

Wu, N., Husile, H., Yang, L., Cao, Y., Li, X., Huo, W., ... & Wu, Q. (2019). A novel pathogenic variant in OSBPL2 linked to hereditary late-onset deafness in a Mongolian family. BMC Medical Genetics, 20, 1-7.

Wang, H., Lin, C., Yao, J., Shi, H., Zhang, C., Wei, Q., ... & Cao, X. (2019). Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity. Cell Death & Disease, 10(9), 627.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols