Human PCDH10 ELISA Kit (V2LY-0626-LY5136)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.056 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
112.9 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
protocadherin 10
Function
Potential calcium-dependent cell-adhesion protein.
Biological Process
Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Homophilic cell adhesion via plasma membrane adhesion moleculesIEA:Ensembl
Cellular Location
Cell membrane
Topology
Extracellular: 19-715
Helical: 716-736
Cytoplasmic: 737-1040

Zhen, Y., Pavez, M., & Li, X. (2023). The role of Pcdh10 in neurological disease and cancer. Journal of Cancer Research and Clinical Oncology, 149(10), 8153-8164.

Zhang, N., Gao, X., Yuan, Q., Fu, X., Wang, P., Cai, F., ... & Deng, J. (2023). E3 ubiquitin ligase RNF180 prevents excessive PCDH10 methylation to suppress the proliferation and metastasis of gastric cancer cells by promoting ubiquitination of DNMT1. Clinical Epigenetics, 15(1), 77.

Yang, J., Hou, C., Wang, H., Perez, E. A., Do-Umehara, H. C., Dong, H., ... & Liu, J. (2023). Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10. Cancer Letters, 555, 216025.

Ferri, S. L., Dow, H. C., Schoch, H., Lee, J. Y., Brodkin, E. S., & Abel, T. (2021). Age-and sex-specific fear conditioning deficits in mice lacking Pcdh10, an autism associated gene. Neurobiology of learning and memory, 178, 107364.

Jao, T. M., Fang, W. H., Ciou, S. C., Yu, S. L., Hung, Y. L., Weng, W. T., ... & Yang, Y. C. (2021). PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. Cancer letters, 499, 290-300.

Zhou, J., Wang, L., Sun, Q., Chen, R., Zhang, C., Yang, P., ... & Sun, Y. (2021). Hsa_circ_0001666 suppresses the progression of colorectal cancer through the miR‐576‐5p/PCDH10 axis. Clinical and translational medicine, 11(11), e565.

Seo, S. I., Yoon, J. H., Byun, H. J., & Lee, S. K. (2021). HOTAIR induces methylation of PCDH10, a tumor suppressor gene, by regulating DNMT1 and sponging with miR-148b in gastric adenocarcinoma. Yonsei medical journal, 62(2), 118.

Shi, B., Mao, S., Xu, L., Li, Y., Sun, X., Liu, Z., ... & Qiu, Y. (2020). Quantitation analysis of PCDH10 methylation in adolescent idiopathic scoliosis using pyrosequencing study. Spine, 45(7), E373-E378.

Curia, M. C., Fantini, F., Lattanzio, R., Tavano, F., Di Mola, F., Piantelli, M., ... & Cama, A. (2019). High methylation levels of PCDH10 predict poor prognosis in patients with pancreatic ductal adenocarcinoma. BMC cancer, 19, 1-11.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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