Human PRODH ELISA Kit (V2LY-0626-LY5067)

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Tested Data
Request for COA
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Basic Information

Sensitivity
0.0045 ng/mL
Detection Range
0.01-2 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
68.0 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
proline dehydrogenase (oxidase) 1
Function
Converts proline to delta-1-pyrroline-5-carboxylate.
Biological Process
4-hydroxyproline catabolic processManual Assertion Based On ExperimentTAS:BHF-UCL
Intrinsic apoptotic signaling pathway in response to oxidative stress1 PublicationNAS:UniProtKB
Positive regulation of cell deathManual Assertion Based On ExperimentIDA:ParkinsonsUK-UCL
Proline catabolic processTAS:Reactome
Proline catabolic process to glutamateManual Assertion Based On ExperimentIBA:GO_Central
Proline metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Mitochondrion matrix
Involvement in disease
Hyperprolinemia 1 (HYRPRO1):
An inborn error of proline metabolism resulting in elevated levels of proline in the plasma and urine. The disorder is generally benign and most affected individuals are clinically asymptomatic. Some patients, however, have neurologic manifestations, including epilepsy and intellectual disability. Association with certain forms of schizophrenia have been reported.
Schizophrenia 4 (SCZD4):
A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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