Human Recombinant ANTXR2 protein, hFc Tag (V2LY-0526-LY2130)

Name: Human Recombinant ANTXR2 protein, hFc Tag
SKU: V2LY-0526-LY2130
Rating: 5 (1 reviews)

See all ANTXR2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Human

Tag

hFc Tag

Protein Construction

This product is Human Recombinant ANTXR2 protein, hFc Tag consist of Amino Acid: 1-317 and predicts a molecular mass of 57.4 kDa.

Molecule Mass

57.4 kDa

Sequence

Amino Acid: 1-317

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>85% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile Tris, NaCl, Glutathione, EDTA, DTT, PMSF, Glycerol

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Anthrax Toxin Receptor 2

Function

Necessary for cellular interactions with laminin and the extracellular matrix.

Biological Process

Toxin transport Source: GO_Central

Cellular Location

Isoform 1: Cell membrane. Expressed at the cell surface.
Isoform 2: Endoplasmic reticulum membrane. Expressed predominantly within the endoplasmic reticulum and not at the plasma membrane.
Isoform 3: Secreted

Involvement in disease

Hyaline fibromatosis syndrome (HFS): An autosomal recessive syndrome characterized by abnormal growth of hyalinized fibrous tissue usually affecting subcutaneous regions on the scalp, ears, neck, face, hands, and feet. The lesions appear as pearly papules or fleshy nodules. Additional features include gingival hypertrophy, progressive joint contractures resulting in severe limitation of mobility, osteopenia, and osteoporosis. Disease severity is variable. Some individuals manifest symptoms in infancy and have additional visceral or systemic involvement. Hyaline deposits in multiple organs, recurrent infections and intractable diarrhea often lead to early death. Surviving children may suffer from severely reduced mobility due to joint contractures. Other patients have later onset of a milder disorder affecting only the face and digits.

Topology

Extracellular: 34-318 aa
Helical: 319-341 aa
Cytoplasmic: 342-489 aa

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Recombinant ANTXR2 protein, hFc Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Recombinant ANTXR2 protein, hFc Tag (CAT#: V2LY-0526-LY7812)

Mouse Recombinant ANTXR2 protein, His Tag (CAT#: V2LY-0526-LY7813)

Related Products

Mouse Recombinant ANTXR2 protein, hFc Tag (CAT#: V2LY-0526-LY7812)

Mouse Recombinant ANTXR2 protein, His Tag (CAT#: V2LY-0526-LY7813)

Mouse Anti-ANTXR2 Recombinant Antibody (CBYC-A621) (CAT#: CBMAB-A2869-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry