Human Recombinant APEG1 protein, His Tag (V2LY-0526-LY2136)

Name: Human Recombinant APEG1 protein, His Tag
SKU: V2LY-0526-LY2136
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant APEG1 protein, His Tag consist of Amino Acid: 1-113 and predicts a molecular mass of 14 kDa.

Molecule Mass

14 kDa

Sequence

Amino Acid: 1-113

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>85% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

SPEG Complex Locus

Function

Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells.

Biological Process

Biological Process muscle cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process muscle organ developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process protein phosphorylationIEA:InterPro

Cellular Location

Isoform 3
Nucleus

Involvement in disease

Myopathy, centronuclear, 5 (CNM5):
A form of centronuclear myopathy, a congenital muscle disorder characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles. It may also affect distal muscles. Weakness may be present during childhood or adolescence or may not become evident until the third decade of life. Ptosis is a frequent clinical feature. The most prominent histopathologic features include high frequency of centrally located nuclei in muscle fibers not secondary to regeneration, radial arrangement of sarcoplasmic strands around the central nuclei, and predominance and hypotrophy of type 1 fibers. CNM5 features include severe neonatal hypotonia with respiratory insufficiency, difficulty feeding, and delayed motor development. Some patients die in infancy, and some develop dilated cardiomyopathy.

PTM

May be autophosphorylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

SPEG Matched Antibody Pair (1128) (CAT#: APMAB-1128LY)

Antibody Pairs

SPEG Matched Antibody Pair (1128) (CAT#: APMAB-1128LY)

Related Products

Mouse Anti-SPEG Recombinant Antibody (CBXS-4433) (CAT#: CBMAB-S1675-CQ)

Mouse Anti-SPEG Recombinant Antibody (2C2-2C7) (CAT#: CBMAB-A0401-LY)

SPEG Matched Antibody Pair (1128) (CAT#: APMAB-1128LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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