Human Recombinant CDKL2 protein, His Tag (V2LY-0526-LY3066)

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Basic Information

Expressed Host
Baculovirus-Insect Cells
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant CDKL2 protein, His Tag consist of Amino Acid: 1-493 and predicts a molecular mass of 58.3 kDa.
Molecule Mass
58.3 kDa
Sequence
Amino Acid: 1-493
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>80% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
Cyclin Dependent Kinase Like 2
Biological Process
Protein phosphorylation Source: GO_Central
Sex differentiation Source: ProtInc
Signal transduction Source: ProtInc
Cellular Location
Nucleus; Cytoplasm

Yi, R., Yang, S., Liao, Y., Hu, Z., Long, H., Zeng, Y., ... & Wu, Z. (2020). Decreased CDKL2 expression is correlated with the progression and poor prognosis of glioma. Pathology-Research and Practice, 216(5), 152920.

Shao, Q., Wang, F., Xu, Y., Zhang, X., Tang, W., Feng, Y., & Li, Y. (2020). CDKL2 Is Associated with HER2 Status and Overall Survival in Gastric Cancer: Comparative Analysis of CDKL2 Protein Expression and Gene Copy Number. BioMed Research International, 2020.

Zhou, Y., Qiu, X. P., Li, Z. H., Zhang, S., Rong, Y., & Yang, G. H. (2019). Clinical significance of aberrant cyclin-dependent kinase-like 2 methylation in hepatocellular carcinoma. Gene, 683, 35-40.

Zhao, Y., Yang, J., Liu, Y., Fan, J., & Yang, H. (2019). HSV-2-encoded miRNA-H4 regulates cell cycle progression and Act-D-induced apoptosis in HeLa Cells by targeting CDKL2 and CDKN2A. Virologica Sinica, 34(3), 278-286.

Fang, C. L., Uen, Y. H., Chen, H. K., Hseu, Y. C., Lin, C. C., Hung, S. T., ... & Lin, K. Y. (2018). Loss of cyclin‐dependent kinase‐like 2 predicts poor prognosis in gastric cancer, and its overexpression suppresses cells growth and invasion. Cancer medicine, 7(7), 2993-3002.

Yi, R., Yang, S., Wen, E., Hu, Z., Long, H., Zeng, Y., ... & Song, Y. (2018). Negative nuclear expression of CDKL2 correlates with disease progression and poor prognosis of glioma. International journal of clinical and experimental pathology, 11(2), 712.

Lin, K. Y., & Uen, Y. H. (2017). Loss of CDKL2 expression correlates with differentiation, stage, and poor prognosis of gastric cancer. Annals of Oncology, 28, x12.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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