Human Recombinant CDKL3 protein, GST Tag (V2LY-0526-LY3067)

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Basic Information

Expressed Host
Baculovirus-Insect Cells
Protein Species
Human
Tag
GST Tag
Protein Construction
This product is Human Recombinant CDKL3 protein, GST Tag consist of Amino Acid: Full Length and predicts a molecular mass of 98 kDa.
Molecule Mass
98 kDa
Sequence
Amino Acid: Full Length
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
Batch dependent.
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
More Infomation

Target

Full Name
Cyclin Dependent Kinase Like 3
Biological Process
Cellular protein modification process Source: ProtInc
Dendrite extension Source: GO_Central
Negative regulation of axon extension Source: GO_Central
Positive regulation of dendrite morphogenesis Source: GO_Central
Protein phosphorylation Source: GO_Central
Cellular Location
Cytoplasm

Zeng, D. X., Sheng, G. F., Liu, Y. P., Zhang, Y. P., Qian, Z., Li, Z., & Bi, Y. Z. (2021). Cyclin-dependent kinase like 3 promotes triple-negative breast cancer progression via inhibiting the p53 signaling pathway. Neoplasma.

Yan, S., Wei, H., Li, Q., Si, M., Feng, W., & Chen, Z. (2021). CircTP53 promotes colorectal cancer by acting as a miR-876-3p sponge to increase cyclin-dependent kinase-like 3 expression. Cellular Signalling, 78, 109845.

Cui, Y., Yang, Z., Wang, H., Yan, Y., Huang, Q., Gong, Z., ... & Xu, T. (2021). Identification of CDKL3 as a critical regulator in development of glioma through regulating RRM2 and the JNK signaling pathway. Cancer science, 112(8), 3150.

Sun, Q., Zhang, X., Tan, Z., Gu, H., Ding, S., & Ji, Y. (2021). Bone marrow mesenchymal stem cells-secreted exosomal microRNA-205–5p exerts inhibitory effect on the progression of liver cancer through regulating CDKL3. Pathology-Research and Practice, 225, 153549.

He, A., Ma, L., Huang, Y., Zhang, H., Duan, W., Li, Z., ... & Xiang, D. (2020). CDKL3 promotes osteosarcoma progression by activating Akt/PKB. Life science alliance, 3(5).

Zhou, S., Zhang, M., Zhou, C., Wang, W., Yang, H., & Ye, W. (2020). CDKL3 Targets ATG5 to Promote Carcinogenesis of Esophageal Squamous Cell Carcinoma. Frontiers in Oncology, 10, 1602.

Zhang, J., Su, G., Tang, Z., Wang, L., Fu, W., Zhao, S., ... & Xie, X. (2018). Curcumol exerts anticancer effect in cholangiocarcinoma cells via down-regulating CDKL3. Frontiers in physiology, 9, 234.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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