Human Recombinant CPNE1 protein, SUMO Tag (V2LY-0526-LY3354)
Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner (PubMed:14674885).
Exhibits calcium-dependent phospholipid binding properties (PubMed:9430674, PubMed:19539605).
Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner (PubMed:23263657, PubMed:25450385).
May recruit target proteins to the cell membrane in a calcium-dependent manner (PubMed:12522145).
May function in membrane trafficking (PubMed:9430674).
Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit (PubMed:18212740).
Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL (PubMed:18212740).
Glycerophospholipid biosynthetic process Source: Reactome
Lipid metabolic process Source: ProtInc
Negative regulation of DNA binding Source: UniProtKB
Negative regulation of gene expression Source: UniProtKB
Negative regulation of NIK/NF-kappaB signaling Source: UniProtKB
Neuron projection extension Source: UniProtKB
Neutrophil degranulation Source: Reactome
Positive regulation of neuron differentiation Source: UniProtKB
Positive regulation of protein kinase B signaling Source: UniProtKB
Positive regulation of tumor necrosis factor-mediated signaling pathway Source: UniProtKB
Proteolysis Source: UniProtKB
Regulation of I-kappaB kinase/NF-kappaB signaling Source: UniProtKB
Vesicle-mediated transport Source: ProtInc
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Human Recombinant CPNE1 protein (CAT#: V2LY-0526-LY3353)
CPNE1 Matched Antibody Pair (296) (CAT#: APMAB-296LY)
Antibody Pairs
CPNE1 Matched Antibody Pair (296) (CAT#: APMAB-296LY)
Related Products
Mouse Anti-CPNE1 Recombinant Antibody (CBFYC-2162) (CAT#: V2LY-1206-LY970)
CPNE1 Matched Antibody Pair (296) (CAT#: APMAB-296LY)
Human CPNE1 ELISA Kit (CAT#: V2LY-0626-LY3007)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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