Human Recombinant CYGB protein, His Tag (V2LY-0526-LY3485)

Zweier, J. L., Hemann, C., Kundu, T., Ewees, M. G., Khaleel, S. A., Samouilov, A., ... & El-Mahdy, M. A. (2021). Cytoglobin has potent superoxide dismutase function. Proceedings of the National Academy of Sciences, 118(52).

Dat, N. Q., Thuy, L. T. T., Hieu, V. N., Hai, H., Hoang, D. V., Thi Thanh Hai, N., ... & Kawada, N. (2021). Hexa Histidine–Tagged Recombinant Human Cytoglobin Deactivates Hepatic Stellate Cells and Inhibits Liver Fibrosis by Scavenging Reactive Oxygen Species. Hepatology, 73(6), 2527-2545.

De Backer, J., Maric, D., Bosman, M., Dewilde, S., & Hoogewijs, D. (2021). A reliable set of reference genes to normalize oxygen-dependent cytoglobin gene expression levels in melanoma. Scientific reports, 11(1), 1-11.

Zweier, J. L., & Ilangovan, G. (2020). Regulation of nitric oxide metabolism and vascular tone by cytoglobin. Antioxidants & Redox Signaling, 32(16), 1172-1187.

Le Thi Thanh Thuy, H. H., & Kawada, N. (2020). Role of cytoglobin, a novel radical scavenger, in stellate cell activation and hepatic fibrosis. Clinical and molecular hepatology, 26(3), 280.

Okina, Y., Sato-Matsubara, M., Matsubara, T., Daikoku, A., Longato, L., Rombouts, K., ... & Kawada, N. (2020). TGF-β1-driven reduction of cytoglobin leads to oxidative DNA damage in stellate cells during non-alcoholic steatohepatitis. Journal of hepatology, 73(4), 882-895.

De Backer, J., Razzokov, J., Hammerschmid, D., Mensch, C., Hafideddine, Z., Kumar, N., ... & Dewilde, S. (2018). The effect of reactive oxygen and nitrogen species on the structure of cytoglobin: A potential tumor suppressor. Redox biology, 19, 1-10.

Jourd’heuil, F. L., Xu, H., Reilly, T., McKellar, K., El Alaoui, C., Steppich, J., ... & Jourd’heuil, D. (2017). The hemoglobin homolog cytoglobin in smooth muscle inhibits apoptosis and regulates vascular remodeling. Arteriosclerosis, thrombosis, and vascular biology, 37(10), 1944-1955.

Xu, Z. J., Shu, S., Li, Z. J., Liu, Y. M., Zhang, R. Y., & Zhang, Y. (2017). Liuwei Dihuang pill treats diabetic nephropathy in rats by inhibiting of TGF-β/SMADS, MAPK, and NF-kB and upregulating expression of cytoglobin in renal tissues. Medicine, 96(3).

Liu, X., El-Mahdy, M. A., Boslett, J., Varadharaj, S., Hemann, C., Abdelghany, T. M., ... & Zweier, J. L. (2017). Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall. Nature communications, 8(1), 1-14.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols