Human Recombinant FABP1 protein, His Tag (V2LY-0526-LY5288)

Name: Human Recombinant FABP1 protein, His Tag
SKU: V2LY-0526-LY5288
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant FABP1 protein, His Tag consist of Amino Acid: 2-127 and predicts a molecular mass of 15.6 kDa.

Molecule Mass

15.6 kDa

Sequence

Amino Acid: 2-127

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>97% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile Tris, NaCl

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Fatty Acid Binding Protein 1

Research Area

Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes (PubMed:25732850).

Binds cholesterol (PubMed:25732850).

Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity).

Biological Process

Cellular response to hydrogen peroxide Source: UniProtKB
Cellular response to hypoxia Source: UniProtKB
Intestinal absorption Source: Ensembl
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: UniProtKB
Positive regulation of fatty acid beta-oxidation Source: Ensembl
Positive regulation of hydrolase activity Source: Ensembl

Cellular Location

Cytoplasm

Khalifa, O., Al-Akl, N. S., Errafii, K., & Arredouani, A. (2022). Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway. Scientific Reports, 12(1), 1-13.

Yang, F., Gan, L., Pan, J., Chen, Y., Zhang, H., & Huang, L. (2022). Integrated Single-Cell RNA-Sequencing Analysis of Gastric Cancer Identifies FABP1 as a Novel Prognostic Biomarker. Journal of Oncology, 2022.

Cavazza, A., & McPhail, M. J. (2021). Absolutely FABulous? FABP-1 in Non-acetaminophen-related Acute Liver Failure. Digestive Diseases and Sciences, 66(1), 10-11.

Kawakami, R., Matsui, M., Konno, A., Kaneko, R., Shrestha, S., Shrestha, S., ... & Iso, T. (2021). Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury. The Journal of Pathology, 255(4), 362-373.

Valizadeh, M., Aghasizadeh, M., Nemati, M., Hashemi, M., Aghaee-Bakhtiari, S. H., Zare-Feyzabadi, R., ... & Ghayour-Mobarhan, M. (2021). The association between a Fatty Acid Binding Protein 1 (FABP1) gene polymorphism and serum lipid abnormalities in the MASHAD cohort study. Prostaglandins, Leukotrienes and Essential Fatty Acids, 172, 102324.

Valizadeh, M., Aghasizadeh, M., Saberi-Karimian, M., Safari, M., Rohban, M., Bana, H. S., ... & Ghayour-Mobarhan, M. (2021). Association of macro-and micro-nutrients dietary intakes with rs2241883 genetic variants of FABP 1 gene in MASHAD study population. Clinical nutrition ESPEN, 45, 262-266.

Liu, S., Ni, C., Li, Y., Yin, H., Xing, C., Yuan, Y., & Gong, Y. (2021). The Involvement of TRIB3 and FABP1 and Their Potential Functions in the Dynamic Process of Gastric Cancer. Frontiers in molecular biosciences, 8.

Tsai, I. T., Wu, C. C., Hung, W. C., Lee, T. L., Hsuan, C. F., Wei, C. T., ... & Wang, C. P. (2020). FABP1 and FABP2 as markers of diabetic nephropathy. International journal of medical sciences, 17(15), 2338.

Lu, Y. C., Chang, C. C., Wang, C. P., Hung, W. C., Tsai, I. T., Tang, W. H., ... & Hsu, C. C. (2020). Circulating fatty acid-binding protein 1 (FABP1) and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus. International Journal of Medical Sciences, 17(2), 182.

Pi, H., Liu, M., Xi, Y., Chen, M., Tian, L., Xie, J., ... & Gao, F. (2019). Long‐term exercise prevents hepatic steatosis: a novel role of FABP1 in regulation of autophagy‐lysosomal machinery. The FASEB Journal, 33(11), 11870-11883.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

FABP1 Matched Antibody Pair (398) (CAT#: APMAB-398LY)

FABP1 Matched Antibody Pair (399) (CAT#: APMAB-399LY)

FABP1 Matched Antibody Pair (400) (CAT#: APMAB-400LY)

FABP1 Matched Antibody Pair (401) (CAT#: APMAB-401LY)

FABP1 Matched Antibody Pair (402) (CAT#: APMAB-402LY)

FABP1 Matched Antibody Pair (403) (CAT#: APMAB-403LY)

Antibody Pairs

FABP1 Matched Antibody Pair (398) (CAT#: APMAB-398LY)

FABP1 Matched Antibody Pair (399) (CAT#: APMAB-399LY)

FABP1 Matched Antibody Pair (400) (CAT#: APMAB-400LY)

FABP1 Matched Antibody Pair (401) (CAT#: APMAB-401LY)

FABP1 Matched Antibody Pair (402) (CAT#: APMAB-402LY)

FABP1 Matched Antibody Pair (403) (CAT#: APMAB-403LY)

Related Products

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Mouse Anti-FABP1 Recombinant Antibody (CBXF-2557) (CAT#: CBMAB-F0147-CQ)

Mouse Anti-FABP1 Recombinant Antibody (CBXF-0223) (CAT#: CBMAB-F0318-CQ)

Mouse Anti-FABP1 Recombinant Antibody (CBXF-2011) (CAT#: CBMAB-F2626-CQ)

FABP1 Matched Antibody Pair (403) (CAT#: APMAB-403LY)

Mouse Anti-FABP1 Recombinant Antibody (CBHb147) (CAT#: CBMAB-Hb648-LY)

Mouse Anti-FABP1 Recombinant Antibody (CBXF-0226) (CAT#: CBMAB-F1426-CQ)

FABP1 Matched Antibody Pair (400) (CAT#: APMAB-400LY)

FABP1 Matched Antibody Pair (402) (CAT#: APMAB-402LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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