FABP1
This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]
Full Name
Fatty Acid Binding Protein 1
Research Area
Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes (PubMed:25732850).
Binds cholesterol (PubMed:25732850).
Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity).
Binds cholesterol (PubMed:25732850).
Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity).
Biological Process
Cellular response to hydrogen peroxide Source: UniProtKB
Cellular response to hypoxia Source: UniProtKB
Intestinal absorption Source: Ensembl
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: UniProtKB
Positive regulation of fatty acid beta-oxidation Source: Ensembl
Positive regulation of hydrolase activity Source: Ensembl
Cellular response to hypoxia Source: UniProtKB
Intestinal absorption Source: Ensembl
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: UniProtKB
Positive regulation of fatty acid beta-oxidation Source: Ensembl
Positive regulation of hydrolase activity Source: Ensembl
Cellular Location
Cytoplasm
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Anti-FABP1 antibodies
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CompareTarget: FABP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBHb147
Application*: E, WB
Target: FABP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYY-I1820
Application*: WB, IH, IF
Target: FABP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBXF-2790
Application*: WB, IH
Target: FABP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2011
Application*: WB
Target: FABP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Rat
Clone: CBXF-1371
Application*: WB, IH
Target: FABP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Mouse, Rat
Clone: CBXF-0226
Application*: WB, IH
Target: FABP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXF-0222
Application*: E, WB
Target: FABP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXF-0221
Application*: E, WB
Target: FABP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXF-0223
Application*: WB, E, IP
Target: FABP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-2557
Application*: WB, IP, IF, E, P
Target: FABP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYCL-120
Application*: WB, IP, IF, E, P
Target: FABP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1022
Application*: WB, E, IP
Target: FABP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBXF-2051
Application*: WB, F
Target: FABP1
Specificity: Human
Target: FABP1
Specificity: Human
Target: FABP1
Specificity: Human
Target: FABP1
Specificity: Human
Target: FABP1
Specificity: Human
Target: FABP1
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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