Human Recombinant HERC4, Active protein, GST Tag (V2LY-0526-LY4541)

Mutlu, M., Schmidt, I., Morrison, A. I., Goretzki, B., Freuler, F., Begue, D., ... & Guerini, D. (2023). A novel HERC4-dependent glue degrader targeting STING. BioRxiv, 2023-02.

Zhang, Z., Li, M., Lin, P., Ren, Y., He, Y., Wang, S., ... & Mao, X. (2023). The ubiquitin ligase HERC4 suppresses MafA transcriptional activity triggered by GSK3β in myeloma by atypical K63-linked polyubiquitination. Journal of Biological Chemistry, 299(5).

Huang, F., Tang, X., Sun, T., Wang, G., Ru, Q., & Zheng, Y. (2021). SAV1, regulated by HERC4, inhibits the proliferation, migration, and invasion of hepatocellular carcinoma. Translational Cancer Research, 10(1), 349.

Sun, X., Sun, B., Cui, M., & Zhou, Z. (2019). HERC4 exerts an anti-tumor role through destabilizing the oncoprotein Smo. Biochemical and biophysical research communications, 513(4), 1013-1018.

Xu, Y., Ji, K., Wu, M., Hao, B., Yao, K. T., & Xu, Y. (2019). A miRNA-HERC4 pathway promotes breast tumorigenesis by inactivating tumor suppressor LATS1. Protein & cell, 10(8), 595-605.

Jiang, W., Yao, X., Shan, Z., Li, W., Gao, Y., & Zhang, Q. (2019). E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation. Journal of Molecular Cell Biology, 11(9), 791-803.

Yang, G., Hamadeh, I. S., Katz, J., Riva, A., Lakatos, P., Balla, B., ... & Gong, Y. (2018). SIRT1/HERC4 locus associated with bisphosphonate‐induced osteonecrosis of the jaw: an exome‐wide association analysis. Journal of Bone and Mineral Research, 33(1), 91-98.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols