Human Recombinant KDM4C protein, GST Tag (V2LY-0526-LY5145)

Pan, H. C., Chen, Y. H., Fang, W. C., Wu, V. C., & Sun, C. Y. (2022). Essential roles of the histone demethylase KDM4C in renal development and acute kidney injury. International Journal of Molecular Sciences, 23(16), 9318.

Lin, C. Y., Wang, B. J., Fu, Y. K., Huo, C., Wang, Y. P., Chen, B. C., ... & Chuu, C. P. (2022). Inhibition of KDM4C/c‐Myc/LDHA signalling axis suppresses prostate cancer metastasis via interference of glycolytic metabolism. Clinical and Translational Medicine, 12(3).

Jie, X., Chen, Y., Zhao, Y., Yang, X., Xu, Y., Wang, J., ... & Wu, G. (2022). Targeting KDM4C enhances CD8+ T cell mediated antitumor immunity by activating chemokine CXCL10 transcription in lung cancer. Journal for Immunotherapy of Cancer, 10(2).

Jie, X., Fong, W. P., Zhou, R., Zhao, Y., Zhao, Y., Meng, R., ... & Xu, S. (2021). USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription. Cell Death & Differentiation, 28(7), 2095-2111.

Wang, J., Li, Y., Wang, P., Han, G., Zhang, T., Chang, J., ... & Zhang, H. (2020). Leukemogenic chromatin alterations promote AML leukemia stem cells via a KDM4C-ALKBH5-AXL signaling axis. Cell stem cell, 27(1), 81-97.

Chen, Y., Fang, R., Yue, C., Chang, G., Li, P., Guo, Q., ... & Huang, S. (2020). Wnt-induced stabilization of KDM4C is required for Wnt/β-catenin target gene expression and glioblastoma tumorigenesis. Cancer research, 80(5), 1049-1063.

Kato, H., Kushima, I., Mori, D., Yoshimi, A., Aleksic, B., Nawa, Y., ... & Ozaki, N. (2020). Rare genetic variants in the gene encoding histone lysine demethylase 4C (KDM4C) and their contributions to susceptibility to schizophrenia and autism spectrum disorder. Translational psychiatry, 10(1), 421.

Lin, C. Y., Wang, B. J., Chen, B. C., Tseng, J. C., Jiang, S. S., Tsai, K. K., ... & Chuu, C. P. (2019). Histone demethylase KDM4C stimulates the proliferation of prostate cancer cells via activation of AKT and c-Myc. Cancers, 11(11), 1785.

Hung, K. H., Woo, Y. H., Lin, I. Y., Liu, C. H., Wang, L. C., Chen, H. Y., ... & Lin, K. I. (2018). The KDM4A/KDM4C/NF-κB and WDR5 epigenetic cascade regulates the activation of B cells. Nucleic Acids Research, 46(11), 5547-5560.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols