Human Recombinant KLC1-ALK, Active protein, GST Tag (V2LY-0526-LY5183)

Antón, Z., Weijman, J. F., Williams, C., Moody, E. R., Mantell, J., Yip, Y. Y., ... & Dodding, M. P. (2021). Molecular mechanism for kinesin-1 direct membrane recognition. Science Advances, 7(31), eabg6636.

Saez, T. M., Fernandez Bessone, I., Rodriguez, M. S., Alloatti, M., Otero, M. G., Cromberg, L. E., ... & Falzone, T. L. (2020). Kinesin-1-mediated axonal transport of CB1 receptors is required for cannabinoid-dependent axonal growth and guidance. Development, 147(8), dev184069.

Moamer, A., Hachim, I. Y., Binothman, N., Wang, N., Lebrun, J. J., & Ali, S. (2019). A role for kinesin-1 subunits KIF5B/KLC1 in regulating epithelial mesenchymal plasticity in breast tumorigenesis. EBioMedicine, 45, 92-107.

Mórotz, G. M., Glennon, E. B., Greig, J., Lau, D. H., Bhembre, N., Mattedi, F., ... & Miller, C. C. (2019). Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer’s disease and regulates axonal transport and processing of the amyloid precursor protein. Acta neuropathologica communications, 7, 1-13.

Cockburn, J. J., Hesketh, S. J., Mulhair, P., Thomsen, M., O'Connell, M. J., & Way, M. (2018). Insights into kinesin-1 activation from the crystal structure of KLC2 bound to JIP3. Structure, 26(11), 1486-1498.

Nguyen, T. Q., Aumont-Nicaise, M., Andreani, J., Velours, C., Chenon, M., Vilela, F., ... & Ménétrey, J. (2018). Characterization of the binding mode of JNK-interacting protein 1 (JIP1) to kinesin-light chain 1 (KLC1). Journal of Biological Chemistry, 293(36), 13946-13960.

Pernigo, S., Chegkazi, M. S., Yip, Y. Y., Treacy, C., Glorani, G., Hansen, K., ... & Steiner, R. A. (2018). Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors. Elife, 7, e38362.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols