Human Recombinant PFN2 protein, His Tag (V2LY-0526-LY6332)

Name: Human Recombinant PFN2 protein, His Tag
SKU: V2LY-0526-LY6332
Rating: 5 (1 reviews)

See all PFN2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant PFN2 protein, His Tag consist of Amino Acid: 1-140 and predicts a molecular mass of 16.9 kDa.

Molecule Mass

16.9 kDa

Sequence

Amino Acid: 1-140

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>90% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Profilin 2

Function

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Biological Process

Actin cytoskeleton organizationIEA:InterPro
Modification of postsynaptic actin cytoskeletonIEA:Ensembl
Negative regulation of actin filament polymerizationManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of epithelial cell migrationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of ruffle assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of actin filament bundle assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of actin filament polymerizationManual Assertion Based On ExperimentIGI:UniProtKB
Positive regulation of ATP-dependent activityManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of peptidyl-serine phosphorylationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of stress fiber assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Protein stabilizationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of actin filament polymerizationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of synaptic vesicle exocytosisIEA:Ensembl

Cellular Location

Cytoplasm, cytoskeleton

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Recombinant PFN2 protein, His Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-PFN2 Recombinant Antibody (CBYC-P314) (CAT#: CBMAB-P1529-YC)

Mouse Anti-PFN2 Recombinant Antibody (6G3) (CAT#: CBMAB-P1528-YC)

Mouse Anti-PFN2 Recombinant Antibody (CF335) (CAT#: CBMAB-FT163LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry