Human Recombinant PKDCC protein, GST Tag (V2LY-0526-LY7635)

Go to compare Compare Online Inquiry
Request for COA
Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host
Baculovirus-Insect Cells
Protein Species
Human
Tag
GST Tag
Protein Construction
This product is Human Recombinant PKDCC protein, GST Tag consist of Amino Acid: 129-end and predicts a molecular mass of 69 kDa.
Molecule Mass
69 kDa
Sequence
Amino Acid: 129-end
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
Batch dependent.
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
More Infomation

Target

Full Name
Protein Kinase Domain Containing, Cytoplasmic
Function
Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29 (PubMed:25171405).
Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation (PubMed:25171405).
May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation. May be indirectly involved in protein transport from the Golgi apparatus to the plasma membrane (By similarity).
Biological Process
Bone mineralizationIEA:Ensembl
Cell differentiationIEA:UniProtKB-KW
Embryonic digestive tract developmentISS:UniProtKB
Limb morphogenesisIEA:Ensembl
Lung alveolus developmentISS:UniProtKB
Multicellular organism growthIEA:Ensembl
Negative regulation of Golgi to plasma membrane protein transportISS:UniProtKB
Peptidyl-tyrosine phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of bone mineralizationISS:UniProtKB
Positive regulation of chondrocyte differentiationISS:UniProtKB
Protein transportIEA:UniProtKB-KW
Roof of mouth developmentISS:UniProtKB
Skeletal system developmentManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Secreted
Golgi apparatus
Involvement in disease
Secreted 1 Publication
Golgi apparatus:
An autosomal recessive skeletal dysplasia characterized by rhizomelic shortening of limbs as well as variable dysmorphic features, including macrocephaly, short neck, micrognathia, mild proptosis, downslanting palpebral fissures, depressed or broad nasal bridge and long philtrum.
PTM
N-glycosylated.
Phosphorylated on tyrosines; probably via autophosphorylation.
Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Human Recombinant PKDCC protein, GST Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.