Human Recombinant PKLR protein, His Tag (V2LY-0526-LY6211)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Cellular response to epinephrine stimulusIEA:Ensembl
Cellular response to insulin stimulusManual Assertion Based On ExperimentIBA:GO_Central
Glycolytic processManual Assertion Based On ExperimentIBA:GO_Central
Pyruvate biosynthetic processIEA:Ensembl
Response to ATPIEA:Ensembl
Response to cAMPIEA:Ensembl
Response to glucoseIEA:Ensembl
Response to heatIEA:Ensembl
Response to hypoxiaIEA:Ensembl
Response to lithium ionIEA:Ensembl
Response to nutrientIEA:Ensembl
cytosol
extracellular exosome
Autosomal dominant phenotype characterized by increase of red blood cell ATP.
Pyruvate kinase deficiency of red cells (PKRD):
A frequent cause of hereditary non-spherocytic hemolytic anemia. Clinically, pyruvate kinase-deficient patients suffer from a highly variable degree of chronic hemolysis, ranging from severe neonatal jaundice and fatal anemia at birth, severe transfusion-dependent chronic hemolysis, moderate hemolysis with exacerbation during infection, to a fully compensated hemolysis without apparent anemia.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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