FC, ICC, IF, WB
Full length human recombinant protein of human PKLR (NP_000289) produced in HEK293T cell
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).
PK1; PKL; PKR; PKRL; RPK