Human Recombinant PPM1F protein, GST Tag (V2LY-0526-LY6268)

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Basic Information

Expressed Host
E. coli
Protein Species
Human
Tag
GST Tag
Protein Construction
This product is Human Recombinant PPM1F protein, GST Tag consist of Amino Acid: Full Length and predicts a molecular mass of 74 kDa.
Molecule Mass
74 kDa
Sequence
Amino Acid: Full Length
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
Batch dependent.
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
Sodium phosphate, NaCl
Preservative
None
Storage
Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
More Infomation

Target

Full Name
PPM1F
Function
Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis.
Biological Process
Cellular response to xenobiotic stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Intrinsic apoptotic signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of cell-cell adhesion mediated by cadherinManual Assertion Based On ExperimentIMP:BHF-UCL
Negative regulation of peptidyl-serine phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of protein kinase activityManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of protein kinase activity by regulation of protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of protein transportManual Assertion Based On ExperimentIMP:BHF-UCL
Negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIMP:UniProtKB
Peptidyl-serine dephosphorylationManual Assertion Based On ExperimentIMP:BHF-UCL
Peptidyl-threonine dephosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of cell migrationManual Assertion Based On ExperimentIGI:ARUK-UCL
Positive regulation of cell-substrate adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of chemotaxisManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic processManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of epithelial cell migrationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of focal adhesion assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of gene expressionManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of growthManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of stress fiber assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of protein localizationManual Assertion Based On ExperimentIMP:BHF-UCL
Cellular Location
cytosol
nucleus
perinuclear region of cytoplasm
protein-containing complex
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For research use only. Not intended for any clinical use.

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