Human Recombinant RAB6A protein, His Tag (V2LY-0526-LY6437)

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Basic Information

Expressed Host
E. coli
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant RAB6A protein, His Tag consist of Amino Acid: 1-208 and predicts a molecular mass of 25.8 kDa.
Molecule Mass
25.8 kDa
Sequence
Amino Acid: 1-208
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>85% as determined by SDS-PAGE
Endotoxin
Please contact us for more information.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
RAB6A, Member RAS Oncogene Family
Function
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Involved in COPI-independent retrograde transport from the Golgi to the ER (PubMed:25962623).
Biological Process
Biological Process antigen processing and presentationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process early endosome to Golgi transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process intra-Golgi vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process minus-end-directed organelle transport along microtubuleManual Assertion Based On ExperimentTAS:BHF-UCL
Biological Process neuron projection developmentManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process peptidyl-cysteine methylationManual Assertion Based On ExperimentIDA:MGI
Biological Process protein localization to Golgi apparatusManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein localization to Golgi membraneManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIBA:GO_Central
Biological Process retrograde vesicle-mediated transport, Golgi to endoplasmic reticulumManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Golgi apparatus membrane
BICD2 facilitates its targeting to Golgi apparatus membrane.
Isoform 1
Golgi apparatus membrane
Isoform 2
Golgi apparatus membrane
PTM
Prenylated.
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For research use only. Not intended for any clinical use.

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