Human Recombinant RHOD (Mature form), Active protein, His Tag (V2LY-0526-LY6540)

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Basic Information

Expressed Host
E. coli
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant RHOD (Mature form), Active protein, His Tag consist of Amino Acid: 1-207 and predicts a molecular mass of 23 kDa.
Molecule Mass
23 kDa
Sequence
Amino Acid: 1-207
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
Batch dependent.
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
More Infomation

Target

Full Name
ras homolog gene family, member D
Function
Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution.
Biological Process
Biological Process actin filament bundle assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process actin filament organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cortical cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process establishment or maintenance of cell polarityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process focal adhesion assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process lamellipodium assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of cell adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of cell migrationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of cell shapeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of small GTPase mediated signal transductionTAS:Reactome
Biological Process Rho protein signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell membrane
Early endosome
Colocalizes with RAB5 to early endosomes (By similarity).
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For research use only. Not intended for any clinical use.

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