Human Recombinant SETD4 protein, GST Tag (V2LY-0526-LY6733)

Name: Human Recombinant SETD4 protein, GST Tag
SKU: V2LY-0526-LY6733
Rating: 5 (1 reviews)

See all SETD4 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant SETD4 protein, GST Tag consist of Amino Acid: Full Length and predicts a molecular mass of 62 kDa.

Molecule Mass

62 kDa

Sequence

Amino Acid: Full Length

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

Batch dependent.

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

Tris, NaCl, Glutathione, EDTA, DTT, PMSF, Glycerol

Preservative

None

Storage

Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

More Infomation

Target

Full Name

SET Domain Containing 4

Function

Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response (PubMed:31308046).
Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively), leading to activate the transcription of pro-inflammatory cytokines IL6 and TNF-alpha (By similarity).
Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3), thereby promoting heterochromatin formation (PubMed:31308046).
Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) (By similarity).

Biological Process

Biological Process histone H3-K4 dimethylationISS:UniProtKB
Biological Process histone H3-K4 monomethylationISS:UniProtKB
Biological Process histone H4-K20 trimethylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process inflammatory responseIEA:UniProtKB-KW
Biological Process peptidyl-lysine monomethylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process peptidyl-lysine trimethylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of inflammatory responseISS:UniProtKB
Biological Process positive regulation of interleukin-6 productionISS:UniProtKB
Biological Process positive regulation of tumor necrosis factor productionISS:UniProtKB
Biological Process regulation of cell proliferation in bone marrowISS:UniProtKB

Cellular Location

Cytoplasm, cytosol
Nucleus

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Recombinant SETD4 protein, GST Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human SETD4 ELISA Kit (CAT#: V2LY-0626-LY1042)

Related Products

Mouse Anti-SETD4 Recombinant Antibody (CBXS-2215) (CAT#: CBMAB-S4977-CQ)

Human SETD4 ELISA Kit (CAT#: V2LY-0626-LY1042)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry