Human Recombinant STAT5A protein, His Tag (V2LY-0526-LY6972)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Biological Process defense responseManual Assertion Based On ExperimentIBA:GO_Central
Biological Process growth hormone receptor signaling pathway via JAK-STATManual Assertion Based On ExperimentIBA:GO_Central
Biological Process lactationIEA:UniProtKB-KW
Biological Process positive regulation of blood vessel endothelial cell migrationManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process positive regulation of endothelial cell proliferationManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process positive regulation of transcription by RNA polymerase II1 PublicationIC:ComplexPortal
Biological Process receptor signaling pathway via JAK-STATManual Assertion Based On ExperimentIBA:GO_Central
Biological Process reelin-mediated signaling pathwayManual Assertion Based On ExperimentIDA:MGI
Biological Process regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of multicellular organism growthISS:BHF-UCL
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to peptide hormoneManual Assertion Based On ExperimentIBA:GO_Central
Biological Process taurine metabolic processISS:BHF-UCL
Nucleus
Translocated into the nucleus in response to phosphorylation.
Activated KIT promotes phosphorylation on tyrosine residues and subsequent translocation to the nucleus (PubMed:21135090).
Tyrosine phosphorylated in response to constitutively activated FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).
Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for maximal transcriptional activity (By similarity).
Tyrosine phosphorylated in response to signaling via activated FLT3; wild-type FLT3 results in much weaker phosphorylation than constitutively activated mutant FLT3 (PubMed:14504097).
Alternatively, can be phosphorylated by JAK2 at Tyr-694 (PubMed:12529425).
ISGylated.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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